Co

propionyl CoA carboxylase

ADP, Pi

SCoA

methylmalonyl CoA

methylmalonyl CoA mutase

COO"

SCoA succinyl CoA

SCoA

methylmalonyl CoA

coenzyme A

O"

methyimalonic acid

Figure 10.13. Reactions of propionyl CoA carboxylase (EC 6.4.1.3) and methylmalonyl CoA mutase (EC 5.4.99.2).

deficiency in experimental animals, and chronic exposure to nitrous oxide may cause vitamin B12 deficiency in human beings (Section 10.9.7).

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