WG is an idiopathic systemic inflammatory disease typically presenting with abnormalities affecting the upper and lower respiratory tracts and the kidneys. However, any organ system can be involved (1). WG is often referred to as an "antineutrophil cytoplasmic antibody (ANCA)-associated small-vessel vasculitis," as are microscopic polyangiitis (MPA) and Churg-Strauss syndrome (CSS) (2). In a minority of patients, however, medium- and large-sized vessels can also be affected; the presence of vasculitis is not necessary for the diagnosis; and ANCA may be lacking in a significant number of cases (3). The terminology "ANCA vasculitis" or "ANCA-associated vasculitis" remains controversial because the absence of ANCA in subsets of patients with these diseases suggests that it is not essential for pathogenesis. Nonetheless, it is possible that its presence may play a role in modifying the disease phenotype or severity.

How To Bolster Your Immune System

How To Bolster Your Immune System

All Natural Immune Boosters Proven To Fight Infection, Disease And More. Discover A Natural, Safe Effective Way To Boost Your Immune System Using Ingredients From Your Kitchen Cupboard. The only common sense, no holds barred guide to hit the market today no gimmicks, no pills, just old fashioned common sense remedies to cure colds, influenza, viral infections and more.

Get My Free Audio Book

Post a comment