Complications And Prognosis

Rarely, patients with chronic IK may develop progressive corneal opacification, which decreases visual acuity. Such patients may require corneal transplantation. Cataracts may also occur and require extraction. Serious posterior segment eye disease can lead to decreased visual acuity. The hearing decline is the major debilitating complication of CS. Progression to deafness is frequent and occurs in approximately 25% to 50% of patients. Many patients have benefited from a cochlear implant, which has dramatically improved their quality of life. Vestibular symptoms usually improve with time, but as many as 20% of patients may have persistent oscillopsia.

FIGURE 2 (A) Conjunctival nodule related to sarcoidosis. Note the circumscribed epithelioid inflammatory nodule, without necrosis (noncaseating). (B) Histopathology of a similar nodule. Note inflammation in surrounding areas, including plasma cells. There are no giant cells. Source: (A) Courtesy of Dr. Glenn Jaffe, Duke University Eye Center. (B) Courtesy of Dr. Alan Proia, Duke University School of Medicine, Department of Pathology.

FIGURE 2 (A) Conjunctival nodule related to sarcoidosis. Note the circumscribed epithelioid inflammatory nodule, without necrosis (noncaseating). (B) Histopathology of a similar nodule. Note inflammation in surrounding areas, including plasma cells. There are no giant cells. Source: (A) Courtesy of Dr. Glenn Jaffe, Duke University Eye Center. (B) Courtesy of Dr. Alan Proia, Duke University School of Medicine, Department of Pathology.

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