Monica Morrow Indications
The majority of patients with intraductal carcinoma or Stage I and II invasive cancer are candidates for a partial mastectomy. Absolute contraindications to the procedure are multicentric carcinoma, prior irradiation to the breast region, first or second trimester pregnancy, diffuse indeterminate microcalcifications on a mammogram, and the inability to achieve negative margins after an adequate number of surgical attempts. Relative contraindications are a large tumor-to-breast ratio and scleroderma or systemic lupus. Patients with invasive carcinoma who are clinically node negative should have their axillary nodal status determined by sentinel node biopsy or axillary dissection. Those who are clinically node positive require axillary dissection.
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