Lo Oo On

LAD Route Measure Result Comment Reference

> 20 p.o. Latency to start t burying

Duration of burying |

>10 i.p. Number of licks i.p. Duration vocali- ! zations p.o. % open arm time -

% open arm antries -

Head dips -

Aborted open 4-arm attempts

Anxiolytic-like, although no single dose was significant Anxiolytic-like, although no single dose was significant No effect under basal conditions Anxiolytic-like under stressful condition No effect on conflict behaviour under basal conditions Anxiolytic-like

Anxiolytic-like under basal conditions, but only in the attempts measure

Heinrichs et al., 2002

Heinrichs et al, 2002

Chaki et al, 2003

Chaki et al, 2003

Chaki et al, 2003

Griebel et al, 2000 Griebel et al, 2002

Social defeat Mouse, CD 1, 10-30 male

Light/dark / box

Mouse defence battery

4-plate test / Lick suppres- /

Passive avoidance

Environment previously paired with shock

Mouse, BALB/c, 1-30 male

Mouse, NMRI, 0.3-10 male

Rat, male 10-30

Mouse, CD1, male

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