Info

Open arm transitions Open arm time

Illuminated area time

Illuminated area f time 4-

Attempts at entries into lit area Illuminated area ■f time

Stretch attend J, postures relative to vehicle' Latency to emerge Duration staying in tube Latency to emerge Duration staying J, in lube

% novel area time Novel area entries -Attempts at entries I

to novel area Duration interacting f

Rat avoidance Risk assessment (stops when chased) Risk assessment (rat approaches) Defensive attack Contextual defence (escape attempts after exposure to rat)

Anxiolytic-like Okuyama under stressful et al, 1999 condition No effect under Okuvama basal conditions Anxiolytic-like under basal conditions

Anxiolytic-like under stressful condition Anxiolytic-like

No effect under basal conditions Anxiolytic-like under basal conditions (chronic treatment 14 d) Minor effects under basal conditions

Anxiolytic-like

Anxiolytic-like et al, 1999

Griebel et al, 1998

Okuyama et al, 1999

Dubowchik et al, 2003

Arborelius et al, 2000

Arborelius et al, 2000

Griebel et al, 1998

Millan et al, 2001 Griebel et al, 1998

Lick suppres- / sion

Punished / lever pressing

Ultrasonic Environment vocalization previously paired with shock

Fear condi- Environment tioning previously paired with shock

Environment previously paired with shock

Rat.Wistar, male 5-80 Rat, Wistar, male 2.5-10

Rat, Wistar. male 2.5-80 Rat, Wistar, male 1-32

Mouse. BALB/c, 20 male

Environment previously paired with shock +1h restraint prior to training

Passive Environment Rat, Wistar, male 10-100

avoidance previously paired with shock

CRA1000 Elevated plus Antagonism of Rat, Wistar, male 0.1-1

Mouse. BALB/c, 20 male

box male

> 20 i.p. Punished licks

> 10 i.p. Punished responding -

> 80 i.p. Duration vocalizations

No effect on conflict behaviour under basal conditions Anxiolytic-like

No effect on conflict behaviour under basal conditions No effect in adult rats

Griebel et al.. 1998

Millan et al.. 2001 Griebel et al.. 1998

Millan et al.. 2001

10 injec- Freezing (count) J, ted 24 h after training

0 0

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