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Staph Infection Secrets By Dr. Walinski

Discover a Simple 3-Step Program to Permanently Eradicate Mrsa & Staph Infections Without Using Antibiotics. Here is what's provided in Staph Infection Secrets. Get Rid of Your Staph / Mrsa Infection. Best ways to quickly get rid of the most common conditions caused by Mrsa and Staph, such as: Impetigo, Cellulitis, Folliculitis, Boils / Carbuncles and more. An easy remedy for nasal infections than can completely eradicate the presence of the bacteria in less than 7 days. How to treat internal infections using a naturally occurring powerful antibiotic with a proven success rate. Learn how to get the most out of Western medicine learn what kinds of treatment is available and how to work with your doctor for best results.

Staph Infection Secrets By Dr Walinski Summary


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Contents: 82 Pages EBook
Author: Dr. Hubert Walinski
Price: $29.95

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Catecholamine Inotropes Can Resuscitate Antibiotic Damaged Staphylococci

In this investigation (Freestone et al. 2008), we undertook two methodological approaches using norepinephrine and dopamine to investigate whether these ino-tropes were capable of facilitating the recovery and growth of antibiotic-damaged staphylococci (S. epidermidis, S. haemolyticus and two S. aureus strains, Newman and 832-4). We employed the antibiotics rifampin and minocycline as our test antimicrobials, as they are the two most frequently employed antibiotics used to coat catheters, and carried out the analyses in a serum-based culture medium (serumSAPI) that more closely approaches the environment the bacteria would have experienced in vivo. The first experimental approach used a minimum inhibitory concentration (MIC) assay, in which the staphylococci were incubated with norepi-nephrine and dopamine in the presence of increasing concentrations of rifampin or minocycline (up to 100 times the MIC for each antibiotic). Representative data for rifampin is shown in Fig. 8.2 for S....

Staphylococcal infections 251

Staphylococcal infections A group of infections caused by staphylococci bacteria that is characterized by the formation of abscesses in the skin or other organs. Staphylococci, which grow in grapelike clusters, are a common cause of skin infections but they can also cause serious internal disorders. Staphylococcal bacteria are normally found on the skin of most people, but if the bacteria get trapped within the skin by blocked sweat or sebaceous glands, they can cause a wide variety of skin infections including pustules, boils, styes, or carbuncles. The bacteria can cause a severe blistering rash in newborn babies called staphylococcal scalded skin syndrome. Staphylococcal infections are among the most common infections in surgical patients, according to the Centers for Disease Control and Prevention. More troubling still, the percentage of hospital-acquired staph infections that are resistant to antibiotics has risen from under 5 percent in 1982 to more than 25 percent in 1992....

Staphylococcal scalded skin syndrome SSSS

A blistering skin rash in newborns that is caused by toxins on the skin released by staphylococcal bacteria. The disorder primarily affects infants between one to three months of age and occasionally older children and adults. Cause Recently, scientists discovered the cause of this condition to be a toxin-produc-ing strain of Staphylococcus aureus. Infants with poor immunity or kidney problems are more vulnerable to this infection. child abuse in the face of the symptoms of this disease. First symptoms usually include evidence of a primary staph infection, including impetigo, eye infection, ear infection, or sore throat with fever, malaise, or irritability. The skin of the face becomes tender, and the skin around the mouth becomes reddened, weeping, and crusting in a way that resembles potato chips. The trunk also may become involved. Staphylococcus aureus A species of Staphylococcus that is responsible for a number of infections such as the boil, carbuncle, abscess, cellulitis,...

Staphylococcus aureus Burke A Cunha MDab

Antibiotic resistance is natural and intrinsic or it is acquired. Intrinsic or natural resistance refers to the inactivity of an antibiotic beyond its usual spectrum of activity (eg, clindamycin has no activity naturally and intrinsically against aerobic gram-negative bacilli). Acquired resistance is limited to relatively few gram-positive and gram-negative organisms. It is uncommon in anaerobic organisms, atypical pulmonary pathogens, Rickettsiae, and so on. Among the gram-positive organisms, acquired resistance to some antibiotics has been widespread with Streptococcus pneumoniae (eg, macrolides). Vancomycin has increased the prevalence of Enterococcus faecium, that is, of vancomycin-resistant enterococci (VRE). Increasing resistance has appeared in methicillin-resistant Staphylococcus aureus (MRSA) 1-6 .

Staphylococcal Infections in the ICU

Most infections caused by the staphylococci are due to S. aureus, an often antibiotic resistant microbe that possesses a diverse array of virulence factors. However, in recent years and in correlating with increase usage of invasive medical procedures, the more opportunistic pathogen coagulase-negative staphylococci (C-NS), and in particular S. epidermidis, have become one of the most important causes of nosocomial infections (Huebner and Goldman 1999 Geffers et al. 2003). The C-NS constitute a major component of the skin microflora and were for many years regarded as saprophytes, or at least as organisms with no or low virulence. However recently, the C-NS, in particular S. epidermidis, have become recognized as serious nosocomial pathogens associated with indwelling medical devices such as catheters and prosthetic joints Surveys have shown that of the 5 million intravascular catheters employed each year, approximately 250,000 CVC-related bloodstream infections are reported with an...

Catecholamine Inotropes Induce Staphylococcal Growth and Biofilm Formation on Intravascular Catheters

Biofilm Microbial Growth

The requirement for iron in growth is recognized for the vast majority of pathogenic and commensal bacteria including the staphylococci (Ratledge and Dover 2000). Under normal conditions, the human body seeks to severely limit the availability of free iron to approximately 10-18 M through the production of the iron sequestering transferrin (blood) and lactoferrin (mucosal secretions and the gastrointestinal tract), to a concentration of iron that is below the level required to support the growth of bacteria. In an effort to obtain iron from host iron-binding proteins such as transferrin, bacteria have developed a variety of mechanisms including ferric reductase, transferrin and lactoferrin binding proteins, and ferric iron sequestering siderophores (Ratledge and Dover 2000). The importance of iron as a determinant of S. epidermidis biofilm formation has been demonstrated in studies that have employed iron restriction. For example, staphylococcal strains of S. epidermidis which were...

Staphylococcal scalded skin syndrome

Caused by a toxin produced by certain species of staphylococci in contaminated food. Among menstruating women (especially those who use highly absorbent tampons), toxin-producing staph may multiply in the mucous membranes lining the vagina, causing toxic shock syndrome. A separate type of staph infection can cause urinary tract infections. Treatment for these types of bacterial infections usually includes bed rest, painkillers, and an antimicrobial drug that is resistant to penicillinase (an enzyme secreted by many species of Staphylococcus). Surgical drainage of deep abscesses may be necessary. See also hospital-acquired infections vancomycin-resistant enterococci (vre).

Staphylococcal Food Poisoning

Background Staphylococcal food poisoning (SFP) is one of the few causes of bacterial FP that can commonly be attributed to a food handler. Humans frequently carry staphylococci either in an infected site or asymptomatically. Infected sites include wounds and abscesses, which may be the source of large numbers of staphylococci. Asymptomatic sites include throat, nostrils, fingernails, or hair. In general, only coagulase-positive staphylococci (Staphy-lococcus aureus), and only certain types, produce enterotoxin. Rarely, some coagulase-negative strains may occasionally produce toxin. Because the organism is also carried by many animals, outbreaks attributable to inadequate processing of a precon-taminated food can occur also. Growth and survival Staphylococci are killed by normal cooking temperatures. Any staphylococci that survive because of inadequate heat penetration or, more frequently, by postcooking contamination from a food handler will, if it is an enterotoxigenic strain and...

Mrsa Infection

A combination of 4 tea tree oil nasal ointment and 5 tea tree oil body wash was found to be superior to the standard 2 mupirocin nasal ointment and triclosan body wash used for the eradication of methicillin-resistant Staphylococcus aureus (Caelli et al 2000). A recent review concluded that tea tree oil was not statistically superior to the standard treatment mupirocin for MSRA (Flaxman & Griffiths 2005). The paper reported on two RCTs (n 30, n 224), both of which demonstrated that tea tree oil was as effective as mupirocin. In the larger trial 224 patients were given either mupirocin 2 nasal ointment, chlorhexidine gluconate 4 soap and silver 2007 Elsevier Australia sulfadiazine 1 cream or tea tree 10 cream and tea tree 5 body wash for five days (Dryden et al 2004). Rates of MRSA clearance were similar 41 in the tea tree group and 49 using standard treatment. Mupirocin was significantly more effective at clearing nasal carriage (78 ) than tea tree cream (47 ) however, tea tree...

Indications Horseradish

Abrasion (f HOO) Allergy (f1 LIB PED) Alzheimer's (1 COX X15231456) Anorexia (f APA DEM) Arthrosis (f1 APA BGB CAN COX X15231456) Asthma (f1 BGB DEM FNF) Atony (f FEL) Bacillus (1 X10548758) Bacteria (12 HHB HH2 KOM X17260672 X10548758) Bronchosis (f12 APA PHR PH2 SKY X16618018) Bruise (f HOO) Cancer (1 FNF JLH) Cancer, abdomen (f1 FNF JLH) Cancer, breast (f1 FNF) Cancer, colon (f1 FNF JLH X15231456) Cancer, liver (f1 FNF JLH) Cancer, nose (f1 FNF JLH) Cancer, spleen (f1 FNF JLH) Cancer, stomach (f1 FNF JLH) Cancer, skin (f1 FNF JLH WO2) Catarrh (1 KOM PHR X17260672) Chilblain (f GMH) Cholecystosis (f PHR PH2) Cold (f1 DEM SKY) Colic (f APA PH2) Congestion (f1 APA) Cough (f12 GMH PHR PH2) Cramp (f1 HHB WIN) Cystosis (1 LIB PHR) Debility (f BOW) Dental Plaque (f FAD) Diabetes (f DEM LIB) Dropsy (f FEL GMH HHB) Dysmenorrhea (f DEM) Dyspepsia (f PHR PH2 SKY) Dysuria (CAN PED fi PHR) Edema (f BGB CAN) Enterosis (1 PH2 WO2) Epistaxis (f HOO) Escherichia (1 HH2 X17260672 X10548758) Fever (f...

Antifungal And Antibacterial

The in vitro evidence of antifungal and antibacterial activity is overwhelming. In vitro results find that tea tree oil has activity against a range of yeasts and fungi found in common mucosal and skin infections such as Corynebacterlum spp., Klebsiella pneumoniae, Micrococcus spp. (M. luteus, M. varians), Propionlbacterium acnes, Streptococcus pyogenes, Trichomonas vaginalis, Pseudomonas aeruginosa, A. baumannli, Staphylococcus spp. (S. aureus, S. capitis, S. epldermidls, S. haemolyticus, 2007 Elsevier Australia

Crinum asiaticum L Amaryllidaceae Crinum Lily Spider Lily Bawang Tanah

Lantern Flies Pennsylvania 2019

Of injury and inflamed joints. 18 The plant has been used for carbuncles and cancer. 7 In Indonesia, the oiled and heated leaves are useful to treat wounds by poisoned arrows, bites and stings. In Malaysia, poultices of the leaves are applied to swellings, swollen joints, lumbago, pains and in cases of headache and fever. The leaves are also an emollient. In Northwest Solomon Islands, the leaves make a topical treatment for inflammation. 19 In Malaysia, the leaves are used as a rheumatic remedy and to relieve local pain. 18 On Karkar Island and in Simbu, Papua New Guinea, the latex from the leaves is applied to cuts. In India, the leaves are applied to skin diseases and inflammation. 20 The crushed leaves are used to wash piles or mixed with honey and applied to wounds and abscesses. 3 Its seeds are considered purgative and emmenag-ogic. 7 In the Trobriands, Papua New Guinea, the stem fibres are used to stop bleeding and in New Ireland, the milky sap from the stem is used for...

Antibacterial activity

Naidu and co-workers (1990 1991) have identified specific LF-binding proteins in Staphylococcus aureus isolated from human and animal infections as well as among various species of coagulase-negative staphylococci causing bovine mastitis. Apo-bLF at concentrations of 0.1 -0.4 could convert compact colonies of Staphylococcus haemolyticus transient to diffused in soft agar (Godo et al., 1997). This surface-active property of LF has prevented autoaggregation of cocci in compact ball-like colonies by hydrophobic interaction or trypsin-sensitive proteins. In vivo anti-staphylococcal activity of hLF, bLF and bLF hydrolysate was reported in an experimental mouse model (Bhimani et al., 1999). All the LF preparations demonstrated weak in vitro antibacterial activity while holo-LFs showed no activity. LF-treated mice (1 mg, i.v.) when injected with 106 staphylococci, showed 30-50 reduction in kidney infections, and viable bacterial counts in the kidney decreased 5- to 12-fold. The inhibitory...

Shellfish poisoning paralytic 245

Examples of bacterial skin infections include impetigo, ecthyma, folliculitis, boils, carbuncles, erysipelas, scarlet fever, cellulitis, etc. Viral infections with skin symptoms include herpes simplex, chicken-pox, and shingles, warts, measles, german measles, fifth disease, aids, etc.

Functional properties and toxicity

In the 1980s several screening studies (agar overlay technique or dilution technique) with essential oils verified the antibacterial and antifungal activity of the essential oil of thyme. It was shown to inhibit a broad spectrum of bacteria generally Gram-positive bacteria being more sensitive than Gram-negative bacteria (Blakeway, 1986 Farag et al. 1986 Deans and Ritchie, 1987). Also some food-borne pathogens, namely Salmonella enteritidis, Escherichia coli, Staphylococcus aureus, Lysteria monocytogenes and Campylobacter jejuni were tested (Smithpalmer et al., 1998). The latter was found to be the most resistant of the bacteria investigated. In another study it was shown that the antibacterial activity of thyme can be used against periodontopathic bacteria including Actinobacillus, Capnocytophaga, Fuso-bacterium, Eikenella and Bacterioides species, and may therefore be suitable for plaque control (Osawa et al., 1990). Furthermore, the essential oil of thyme showed a wide range of...

Applications To Health Promotion And Disease Prevention

The antimicrobial activity of extracts from Artocarpus heterophyllus seed has been investigated. Reports showed that A. heterophyllus seed extracts did not exhibit good inhibitory activity, despite the traditional use of the plant against antibacterial activity. This indicates that the active compounds are mainly distributed in aerial parts, roots, and rhizomes, but not in the seeds. Karthy et al. (2009) showed that the crude ethanol and methanol extracts of the seed exhibited minimal ( 12 mm) antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) however, Khan and colleagues (2003) reported that the crude methanolic extract of the stem and root barks, stem and root heartwood, leaves, fruits, and seeds of A. heterophyllus, and their subsequent partitioning with petrol, dichloromethane, ethyl acetate, and butanol, gave fractions that exhibited a broad spectrum of antibacterial activity, with the butanol fractions of the root bark and fruits being found to be...

Development of Spoilage Microbiota

The micro-organisms that usually dominate the initial microbiota of fresh carcasses are Gram-negative rods (mainly pseudomonads) and micrococci (mainly Kocuria spp. and Staphylococcus spp.). Furthermore, Gramnegative bacteria such as Acinetobacter spp., Alcaligenes spp., Moraxella spp. and Enterobacteriaceae, and Gram-positive species including spore-forming bacteria, lactic acid-producing bacteria and Brochothrix thermo-sphacta, as well as yeasts and moulds, may also be present in small numbers.

Condylomata acuminata

The infant is also vulnerable to maternal infection while passing through the birth canal. At this time, any active infection in the mother's genital area can have serious repercussions to her child. Conditions acquired in this way include conjunctivitis, genital herpes, or chlamydial infection. Staph, or strep infections, meningitis, hepatitis b, or listeriosis may also be passed on. Cause Most conjunctivitis is caused by bacteria (staphylococci) spread by hand-to-eye contact or by viruses associated with a cold, sore throat, or illness such as measles. Viral conjunctivitis can spread like wildfire through schools and other group settings.

Indications Coriander

Adenopathy (f KAB) Ameba (f PH2) Amenorrhea (f JFM) Anorexia (f2 APA EFS KOM PH2) Arthrosis (f BIB HHB) Asthenia (f BOU) Bacillus (1 HH2 X15612768) Bacteria (1 PH2 X15612768) Biliousness (f BIB DEP SUW) Bleeding (f DEP EGG PH2) BO (f APA) Bron-chosis (f KAB) Burn (f BOU) Cancer (f JLH) Cancer, abdomen (f JLH) Cancer, colon (f JLH) Cancer, sinew (f JLH) Cancer, spleen (f JLH) Cancer, uterus (f JLH) Carbuncle (f BOU DEP) Cardiopathy (f BIB GHA) Catarrh (f BIB) Chickenpox (f PH2 SKJ) Childbirth (f IHB PH2) Cholecocystosis (f PHR) Cholera (f BOU) Colic (f DEP GHA HHB) Condyloma (f JLH) Conjunctivosis (f DEP GHA) Coryza (f KAB) Cough (f IHB PHR PH2) Cramp (f1 BGB BIB PH2) Cystosis (f PH2) Dermatosis (f PHR PH2) Diabetes (f JFM) Diarrhea (f APA EGG HHB) Dysentery (f1 APA PHR PH2) Dyspepsia (f12 APA DEP GHA HHB KOM PH2) Dysuria (f PH2) Edema (f PH2) Enterosis (f2 BGB JLH PHR PH2) Epistaxis (f EGG PH2) Erotomania (f BIB) Erysipelas (f BIB) Erythema (f DEP) Escherichia (1 HH2 X15612768) Fever...

Drugs Used to Treat Infectious Diseases

Benethamine penicillin An antibiotic that is effective against most gram-positive bacteria, such as streptococci, staphylococci, and pneu-mococci. This drug is a derivative of ben-zylpenicillin and can be administered by mouth, although it is usually given as an intramuscular injection. itive bacteria, including streptococci, staphylococci, and pneumococci. (See also penicillin.) clindamycin (Trade name Cleocin) An antibacterial drug used to treat acne and serious anaerobic infections that haven't responded, or are resistant, to other antibiotics. Clindamycin is especially effective against most anaerobic bacteria, including Propionibacterium acnes. It is also an excellent agent against Staphylococcus aureus and streptococcal species. cloxacillin (Trade names Cloxapen, Tegopen) A penicillin-type antibiotic used to treat staphylococcal infections that are resistant to penicillin. Administered by mouth or injection, it should not be taken with acidic fruits or juices or aged cheese....

Antibacterial and Antiviral Activities

Antibacterial properties of H. perforatum extracts were reported by Russian scientists in 1959 (64). The main antibacterial principle was determined to be hyperforin and its chemical structure was elucidated in 1975 (65). Recent studies have shown that hyperforin inhibited growth of certain types of microorganisms. Growth inhibition occurred for all gram-positive bacteria that were tested, though no growth-inhibitory effects were seen in the gram-negative bacteria tested (65). Meticillin-resistant (MRSA) and penicillin-resistant (PRSA) Staphylococcus aureus were especially susceptible to hyperforin. The MRSA strain was shown to be resistant to several types of penicillins, ofloxacin, clindamycin, erythromycin, cephalosporins, and gen-tamicin (65). Little toxicity of purified hyperforin in vitro has been observed in peripheral blood mononuclear cells (65). Oral administration of hyper-forin-containing extract of St. John's wort was well tolerated and this supports the potential...

Nutrition and Sutoxins

Reckeweg was also opposed to the consumption of pork because pigs were fed growth hormones which caused inflammations and tissue swelling in humans.807 Because of its histamine content he also thought that pork caused itching which could induce inflammatory processes such as furuncles, carbuncles, appendicitis, gall disorders, phlebitis, but also fluor albus in women as well as skin disease. Referring to Richard Shope's (life dates unknown) work at the

Common Names Cilician

Bacillus (1 X10548751) Bacteria (1 X10548751) Cough (f1 BIB X10548751) Enterobacter (1 X10548751) Escherichia (1 X10548751) Infection (1 X11962214) Klebsiella (1 X10548751) Listeria (1 X10548751) Mycobacterium (1 X10548751) Proteus (1 X10548751) Pseudomonas (1 X10548751) Staphylococcus (1 X10548751) Wound (f1 BIB X10548751).

New uses for older antibiotics

The combination of increasing resistance among selected gram-positive and gram-negative pathogens has prompted a re-evaluation of the antibiotic armamentarium, because few antimicrobials are effective against previously or newly highly resistant micro-organisms. Among the tetracyclines, doxycy-cline and minocycline maintain their effectiveness in their traditional areas of use (eg, rickettsial infections, ehrlichiosis, Lyme and other spirochetal infections) and against bacterial zoonoses 1,3 . In addition, doxycycline has been useful in treating community-acquired pneumonia, including PRSP strains as prophylaxis or therapy for chloroquine-resistant P falciparum malaria and for treating natural or bioterrorist anthrax or plague. Minocycline has been an effective antistaphylococcal antibiotic. Minocycline has potent anti-S aureus activity and is clinically effective against both MSSA and MRSA. Aside from linezolid, minocycline is the only oral antibiotic preparation that has been shown...

Dengue hemorrhagic fever shock syndrome

Diarrhea usually starts suddenly and lasts between a few hours to two or three days. Diarrhea beginning within six horns of eating usually indicates that the food has been contaminated by toxins from Staphylococcus, clostridium, or E. coli bacteria. If it takes longer (between 12 to 48 hours after eating), the diarrhea is probably from contamination

Indications Desert Date

(f BOU KAB) Bronchosis (f UPW) Bubo (f HDN) Burn (f NAD WO2) Carbuncle (f UPW) Caries (f UPW) Catarrh (f HDN) Childbirth (f WO2) Circumcision fi (BOU) Cold (f DEP HDN) Colic (f BIB KAB NAD UPW) Conjunctivosis (f HDN) Cough (f BIB DEP KAB NAD) Cramp (f HDN) Dermatosis (f KAB) Diabetes (1 WO3) Diarrhea (f HDN) Dysentery (f KAB UPW) Edema (1 X15763372) Fasciolaris (1 X10904170) Fever (f BOU HDN) Freckle (f NAD WO2) Fungus (1 HDN) Gingivosis (f UPW) Guinea Worm (1 WO3) Hemorrhoid (f UPW) Hepatosis (f1 HDN UPW PR15 598) Herpes (1 BIB HDN) High Blood Pressure (1 HDN) Impotence (f UPW) Infection (f BIB) Infection (1 HDN) Infertility (f HDN) Inflammation (f1 HDN X15763372) Insanity (f HDN UPW) Jaundice (f1 UPW PR13 439 X10441790) Leprosy (f UPW) Leukoderma (f BOU KAB) Malaria (f1 BIB BI2 BOU) Mycosis (1 HDN) Pain (f1 BOU HDN X15763372) Paralysis (f UPW) Pertussis (f WO2) Pneumonia (f WO2) Pulmonosis (f WO2) Rheumatism (f BIB UPW) Schistosomiasis (1 HDN 15664459) Shingle (1 HDN) Sleeping...

Participation of Neurotransmitters in Chemical Relations Between Organisms

Kagarlitskii et al. 2003 Oleskin and Kirovskaya 2006 Oleskin 2007). Neurotransmitters participate in the communication with each other for growth, in particular serotonin as an intercellular communication agent accelerating and possibly synchronizing development of the microbial cells. Exogenous serotonin stimulates the growth of yeast Candida guillermondii, and the Gram-positive bacterium Streptococcus faecalis at low concentration near 10-7 M added with a periodicity of 2 h (Strakhovskaya et al. 1993). Photoactivation of the synthesis of endogenous serotonin in cells exposed to UV light at 280-360 nm led to the photostimulation of the same cultivated cells in lag-phase (Strakhovskaya et al. 1991 Belenikina et al. 1991). Exogenous serotonin at 2 x 10-7-10-5 M also accelerates culture growth and induces cell aggregation in E. coli and R. rubrum (Oleskin et al. 1998a, b). Moreover, dopamine and norepinephrine stimulate the growth of E. coli, S. enterica, Y. enterocolitica, and the...

The future of antibiotic therapy

Addition of b-lactamase inhibitors to current b-lactam agents continues to be explored. This approach may reach a saturation point because of the emergence of extended-spectrum b-lactamases. LY333328 is a glycopeptide in which the vancosamine sugar has been derivitized, resulting in activity against vancomycin (glycopeptide)-resistant gram-positive bacteria, including enterococci. This compound possesses bactericidal activity against entero-cocci 49 . L786392 is a carbapenem in which the side chain at the 2 position has been modified to improve affinity of penicillin-binding protein 2a of meth-icillin-resistant staphylococci and penicillin-binding protein 5 of penicillin-resistant E faecium 22 .

Indications Bitter Apple

Bacteria (1 ZUL) Bleeding (f ZUL) Bloat (f BIB) Bronchosis (f HDN) Bruise (f GHA) Burn (f UPW) Calculus (f BIB) Cancer (f1 JLH HDN X15527763) Cancer, lung (f1 JLH X15527763) Carbuncle (f BIB) Carcinoma (f JLH) Caries (f UPW) Catarrh (f UPW) Colic (f HDN) Constipation (f BIB) Cough (f UPW) Cramp (f1 HDN) Craw-craw (f HDN) Dandruff (f HDN ZUL) Dermatosis (f HDN) Diarrhea (f HDN UPW) Dysmenorrhea (f HDN) Dyspepsia (f GHA HDN UPW) Earache (f GHA HDN UPW) Edema (f1 HDN) Enterosis (f ZUL) Epilepsy (f HDN) Epistaxis (f BIB) Epithelioma (f JLH) Fever (f1 HDN) Fungus (1 HDN) Gas (f GHA) Gastrosis (f UPW) Gonorrhea (f HDN) Headache (f HDN) Hematuria (f UPW) Hemorrhoid (f GHA) Hepatoma (1 X11108802) Hepatosis (f1 BIB HDN ZUL) Herpes (f HDN) High Blood Pressure (1 HDN) Infection (f1 HDN ZUL) Infertility (f BIB) Inflammation (f1 HDN) Itch (f BIB) Laryngosis (f UPW) Melanoma (f JLH) Myalgia (f HDN) Mycosis (1 HDN) Nephrosis (f BIB) Neuralgia (f UPW) Neurosis (f HDN) Ophthalmia (f UPW) Pain (f HDN...

Shilpa M Patel MDa Louis D Saravolatz Md Macpb

Cellulitis is a common infectious disease managed by physicians in both primary care and specialty practices, and in inpatient and outpatient settings alike. Because scientific data describing therapeutic trials remain limited, clinical experience has guided treatment. Antibiotic therapy should initially be directed at gram-positive organisms, such as staphylococci and streptococci, as these are the most common organisms responsible for causing

QseBC Two Component System

The chemical structure of AI-3 was not completely elucidated yet. However, the role of epinephrine and norepinephrine has been extensively reported in different strains of E. coli, Salmonella, Staphylococcus, among others. A qseC homologue was shown to contribute to virulence in a mouse infection model of the class A bioterrorism threat agent Francisella tularensis (Weiss et al. 2007). A qseC homologue was also demonstrated to be involved in norepinephrine dependent enhancement of motility and colonization of juvenile pigs by S. enterica serovar Typhimurium (Bearson and Bearson, 2008) and virulence gene expression in this bacterium (Merighi et al. 2006 Merighi et al. 2009).

Advanced Decontamination Technologies Irradiation

Bacterial food-borne illnesses account for an estimated 76 million cases, 325,000 hospitalizations, and 5,000 deaths each year in the United States (CDCP, 2005), and 5,300 food-borne outbreaks in Europe resulted in 5,330 hospitalizations and 24 deaths in 2005 (Aymerich, Picouet, & Monfort, 2008). Major food-borne pathogens of concern include Escherichia coli O157 H7, Campylobacter jejuni coli, Salmonella spp., Listeria monocytogenes, Clostridium botulinum perfringens, Staphylococcus aureus, Aeromonas hydrophylia, and Bacillus cereu, and spoilage microorganisms include Pseudomonas, Acinetobac-ter Moraxella, Aeromonas, Alteromonas putrefaciens, Lactobacillus, and Bro-chothrix thermosphecta (Mead et al., 1999). Staphylococcus aureus Grant, I. R., Nixon, C. R., & Patterson, M. F. (1993). Effect of low-dose irradiation on growth of and toxin production by Staphylococcus aureus and Bacillus cereus in roast beef and gravy. International Journal of Food Microbiology, 18(1), 25-36. Monk, J....

Blood poisoning See septicemia

Boil An inflamed pus-filled section of skin (usually an infected hair follicle) found often on the back of the neck or moist areas such as the armpits and groin. A very large boil is called a carbuncle. Boils are usually caused by infection with the bacterium Staphylococcus aureus, which invades the body through a break in the skin, where it infects a blocked oil gland or hair follicle. When the body's immune system sends in white blood cells to kill the germs, the resulting inflammation produces pus. Bursting a boil might spread the infection. Instead, apply a hot compress for 20 minutes every two hours to relieve discomfort and hasten drainage and healing. After treating a boil, wash hands thoroughly before cooking to guard against staph infection getting into food.

Drug Addicts Hemophiliacs and Children

Bill Gates Workin

The number of nonhomosexual GRID cases continued to rise. By mid-1982, two more hemophiliacs were confirmed to have GRID. Infected intravenous drug users were also becoming more common. Furthermore, there were reports of children of GRID-infected drug addicts showing GRID symptoms from birth. One account told of a seventeen-month-old baby who had oral yeast infections, staphylococcus aureus infections, and an infection of a bacterium called Mycobacterium avian-intracellular, which was usually only seen in birds. Another thirty-week-old infant was suffering from infections including PCP, cryptococcosis, and CMV all hallmarks of GRID. Soon, doctors at the CDC were forced to conclude that GRID was not purely a homosexual disease. Furthermore, the fact that babies could be born with the disease made it clear that, although lifestyle was a risk factor, virtually anyone could contact GRID. As this fact became clear, scientists redoubled their efforts to find the cause of GRID.

Indications Fenugreek

Abscess (f VAD WOI) Acne (f VAD) Adenopathy (f CRC HHB) Aging (f BOW) Alactea (f1 PH2 WOI) Allergy (f PED) Alopecia (1 APA KAP MAD) Anemia (f1 BOU GMH SPI VAD) Anorexia (f12 APA CAN KOM PH2 JAC7 405) Aposteme (f JLH) Arthrosis (1 KOM) Atherosclerosis (1 BGB SKY) Backache (f BOW) Bacteria (1 WOI X15331344) Blepharosis (f VAD) Boil (f BGB GMH KAP) Bronchosis (f APA BOU GHA PH2) Burn (f CRC IHB) Calculus (1 APA) Cancer (f1 APA) Cancer, abdomen (f1 FNF JLH) Cancer, bladder (f1 FNF JLH) Cancer, breast (f1 FNF JLH X15936223) Cancer, cervix (f1 BOW) Cancer, colon (f1 FNF JLH) Cancer, eye (f1 FNF JLH) Cancer, gland (f1 FNF JLH) Cancer, groin (f1 FNF JLH) Cancer, intestine (f1 FNF JLH) Cancer, kidney (f1 FNF JLH) Cancer, liver (f1 FNF JLH) Cancer, parotid (f1 FNF JLH) Cancer, rectum (f1 FNF JLH MAD) Cancer, spleen (f1 FNF JLH) Cancer, stomach (f1 FNF JLH) Cancer, testes (f1 FNF JLH) Cancer, throat (f1 FNF JLH) Cancer, uterus (f1 FNF JLH) Cancer, uvula (f1 FNF JLH) Carbuncle (f GMH KAP)...

Mode of action and development of resistance

Oils, and efflux pumps in the outer membrane have been suggested as possible mechanisms for this resistance (Pattnaik et al., 1995a,b Isken and de Bond, 1998 Mann et al., 2000). Mutants of E. coli and sub-populations of Staph. aureus resistant to pine and tea-tree oil, respectively, have also been reported (Moken et al., 1997 Nelson, 2000).

Stevensjohnson syndrome

Stevens Syndrome Disease

Fluid losses occur with skin detachment, leading to prerenal azotemia and electrolyte imbalances. The skin lesions are usually first colonized by Staphylococcus aureus, followed by gram-negative rods. Patients also enter a hypercatabolic state with insulin resistance, and thermoregulation is impaired. Immunologic function is altered, as well, predisposing these patients to sepsis. Skin disorders presenting with desquamation, exfoliation, or blistering are sometimes misdiagnosed as SJS or TEN. The differential diagnosis of SJS TEN includes exfoliative dermatitis, staphylococcal scalded skin syndrome, acute exanthematous pustulosis, paraneoplastic pemphigus, thermal burns, phototoxic reactions, and pressure blisters.

Future consumer trends

Consumers must rely on the training and diligence of commercial food workers who have assumed the role of assuring the safety of foods during preparation. Safe storage of foods prepared away from home then transported to the point of consumption raises concerns that temperature abuse could lead to re-emergence of some types of low-incidence foodborne illnesses, such as Staphylococcus aureus or Bacillus cereus (Little et al., 2002). These researchers concluded that establishments where the manager had participated in food safety training have less food contamination than those without trained managers. Cohen et al. (2001) evaluated the efficacy of an in-house food safety training program and learned that success was dependent on the motivation of the workers to practice safe food handling behaviors. Workers in food establishments in England, most of whom (95 ) had received some type of food safety training, were surveyed regarding their food handling practices (Clayton et al., 2002)....

Stimulant medications 467

Staphylococcal infection Infections caused by staphylococci bacteria and characterized by the formation of abscesses in the skin or other organs. Staphylococci, which grow in grapelike clusters, are a common cause of skin infections, but they also can cause serious internal disorders. Staphylococcal bacteria are normally found on the skin of most people, but if the bacteria get trapped within the skin by blocked sweat or sebaceous glands, they can cause a wide variety of skin infections including pustules, boils, styes, or carbuncles. The bacteria also can cause a severe blistering rash in newborn babies called scalded Staphylococcal infections are among the most common infections in surgical patients, and the number of hospital-acquired staph infections that are resistant to antibiotics has been steadily rising.

Functional properties

Staphylococcus aureus Allspice had a strong bactericidal effect against Yersinia enterocolitica (Bara and Vanetti, 1995). The minimum inhibitory concentrations ( ) of hexane extracts of allspice for several pathogenic bacteria are given in Table 7.14. (Hirasa and Takemasa, 1998). A study testing thymol (thyme and oregano), eugenol (clove, pimento and cinnamon), menthol and anathole (anise and fennel) on three pathogenic bacteria, Salmonella typhimurium, Staphylococcus aureus and Vibrio parahaemolyticus, showed that all these spice components inhibited the bacteria to different extents. Eugenol was more active than thymol, which was more active than anethole. Eugenol is also sporostatic to Bacillus subtilis at 0.05-0.06 level (Tainter and Grenis, 1993). Allspice was also reported to suppress Escherichia coli, Salmonella enterica and Listeria monocytogenes (Friedman et al., 2002).

Castor Oil Plant Castor Bean

Steve Castor

Traditional Medicinal Uses Its leaf poultice is applied to boils and sores in India to treat headaches and fever in Hawaii. 91 The leaves and roots are used in a decoction for anal prolapse, arthritis, constipation, facial palsy, lymph-adenopathy, strabismus, uteral prolapse, cough, and also as a discutient and expectorant. The heated leaves are applied to gout and swellings as well. 51 The leaves and oil are used for dermatological purposes in Nigeria. 101 Its seeds are used to treat abscesses and skin eruptions, deafness, headache, skin problems, bleeding, constipation, boils, piles and to promote labour. 41 They are rubbed on the temple for headache, powdered for abscesses, boils, and carbuncles. The plant is also used for dogbite, scrofula and several skin infections. The Chinese rub the oil on the body for skin ailments. The seeds are crushed and made into a pulp and rubbed into the palms for palsy, introduced into the urethra in stricture and rubbed on the soles of feet of...

Older antibiotics revisited

The recent interest in rediscovering new applications for older antibiotics has developed because of changes in pathogen distribution and resistance. The use of some older antibiotics has increased because of an increase in infections for which the antibiotic was used, which leads to an increase in usage for some established indications 4,5 . Antibiotic resistance is one of the factors responsible for the resurgence of some older antimicrobials. Among gram-positive organisms, there has been an increase in MRSA colonization and infection. Although pneumococcal infections are not more prevalent, there has been some increase in minimal inhibitory concentrations and decrease in sensitivities. More importantly, a dramatic and serious increase in macrolide-resistant Streptococcus pneumoniae (MRSP) has occurred. Overuse of macrolides and TMP-SMX has resulted in an increase in penicillin-resistant S pneumoniae (PRSP) and MRSP, resulting in multi-drug-resistant pneumococci 3,6 . enterococci in...

Morphology and microflora of intercusp fissures in teeth

Microbiological studies conducted by Jodkowska (32) showed that sealing of intercusp fissures not affected by caries led to a considerable reduction in the number of bacteria. The impact of this treatment on intercusp microflora varied depending on time elapsed after sealing and on the type of applied sealant. In a short time, which means 30 minutes after sealing with Nuva-Seal material, no bacteria growth was observed in 89 of examined samples. In further observation periods, after application of this material, a slow decrease of percentage of aseptic samples was observed, which reached the value of 17 after 18 months. After sealing with Concise BWSS (Brand White Sealant System) a reverse tendency was observed. Nuva-Seal material was more effective in fissure sealing than Concise (BWSS) in a short period immediately after treatment. The efficacy of sealing with this material decreased with time. On the other hand Concise (BWSS), which initially inhibited bacteria growth to a lesser...

Exanthem subitum See Roseola

Eye infections The most common infection of the eye is CONJUNCTIVITIS, also known as pinkeye. Most of these infections are caused by bacteria (such as staphylococci) or by viruses associated with a cold, sore throat, or illness such as MEASLES. Viral conjunctivitis is the version that often appears in schools, sweeping through classrooms in massive epidemics. Newborns may contract a type of conjunctivitis from their mothers during birth. This type of infection may be caused by common bacteria, organisms responsible for GONORRHEA or genital HERPES, or by a

Indications Weeping Willow

Abscess (f DAA ROE) Alopecia (f DEM ROE) Arthrosis (f1 DAW ROE SKJ WOI) Bacillus (1 WOI) Bacteria (1 WOI) Bleeding (f DAA) Boil (f DAA) Cancer (f JLH) Carbuncle (f DAA DAW) Dandruff (f ROE) Dermatosis (f ROE) Diarrhea (f DEM) Dyspnea (f DEM) Enterosis (f ROE) Fever (f1 DEP ROE SKJ WOI) Flu (f ROE) Fungus (1 LMP) Gonorrhea (f DAA DAW) Hoarseness (f DEM) Infection (1 ROE WOI) Jaundice (f DAA DAW) Malaria (f1 DAW ROE) Mycosis (1 LMP) Parasite (f DAA) Rheumatism (f1 DAW ROE SKJ WOI) Sore (f DAW ROE) Staphylococcus (1 ROE) Swelling (f DAA) Worm (f DEP EFS NAD).

Clinical Types and Etiology of Diarrhea

Shigella species Salmonella Campylobacter jejuni Enteroadherent Escherichia coli Enteroinvasive Escherichia coli Enterohemorrhagic Escherichia coli Yersinia enterocolitica Staphylococcus aureas Bacillius cereus Vibrio cholerae non-O group 1 Vibrio parahaemolyticus Listeria monocytogenes Aeromonas hydrophilia Plesliomonas shigelloides Staphylococcus aureus Clostridium perfringens Bacillus cereus

J3 L iiiniiioerJiylphosphojiic

Bacteria, possesses significant activity against P-lactamase staphylococcal producers. Its intrinsic potency is, however, less than that of benzylpenicillin against non-P-lactamase staphylococci, and acid instability precludes the oral usage of methicillin. Cephalosporins are generally less sensitive than penicillins to inactivation by staphylococcal p-lactamase, but may be susceptible to p-lactamases produced by some Gram-negative bacteria. Additional information is provided in Sections, including Table 11.4, and 11.5.3. ceftibuten are non-ester drugs and loracarbef is a new oral carbacephem (sulphur at position 1 replaced by carbon). Loracarbef is highly active against Gram-positive organisms, including staphylococci. The others are characterized by activity against Gram-negative and -positive organisms. None of the drugs is active against Ps. aeruginosa. Attention has thus been focused on other types of P-lactamase inhibitors. One of these, clavulanic acid, was...

The rest is history awakening to the possibilities and confronting the challenges

Susceptible bacteria (an important exception is Enterococcus spp) and have an excellent safety profile. The initial introduction of aqueous penicillin G for treatment of streptococcal and staphylococcal infections in 1941 to 1944 was followed by the emergence of penicillinase-producing Staphylococcus aureus. This finding prompted the development of penicillinase-resistant penicillins (methicillin, oxacillin, and nafcillin), in which an acyl side chain prevents disruption of the b-lactam ring by penicillinase. The aminopenicil-lins (ampicillin, amoxicillin, and bacampicillin) were developed because of the need for antibiotics with activity against gram-negative bacteria. Amino-penicillins initially were effective against Escherichia coli, Proteus mirabilis, Shigella spp, Salmonella spp, Hemophilus spp, and Neisseria spp. Carboxy-penicillins (carbenicillin and ticarcillin) and ureidopenicillins (mezlocillin, azlocillin, and piperacillin) offer additional activity that includes...

Applications For Health Promotion And Disease Prevention

Guava fruits are considered to be ethno-pharmacological medicines, and are commonly utilized to control diarrhea in children. Furthermore, tea made from the leaves of guava trees is used to reduce throat inflammation (Jaiarj et al., 1999), and the aqueous extracts from guava buds are known for their intense activity toward Salmonella, Serratia, and Staphylococcus, which are responsible for diarrhea (Jaiarj et al., 1999). similar to antimicrobial peptides from several other families. Hence, Pg-AMP1, as it has been called, has about 6.0 kDa represented by a length of 55 amino acid residues. When Pg-AMP1 was assayed against gram-negative bacteria, it showed the ability to reduce the growth of Proteus and Klebsiella spp. by 30 and 90 , respectively, at a concentration of 6.5 mM. However, it did not show any antimicrobial activity against gram-positive bacteria, such as Staphylococcus aureus, revealing that Pg-AMP1 has specificity towards gram-negative microorganisms (Pelegrini et al.,...

Antibacterial Effect

Thirteen phenolic glycosides including six new compounds were isolated from seeds of C. tora. The structures of the new compounds, rubrofusarin trigluco-side, nor-rubrofusarin gentiobioside, demethylflavasperone gentiobioside, torachrysone gentiobioside, torachrysone tetraglucoside, and torachrysone apioglucoside, were deduced on the basis of spectroscopic and chemical evidence. The effect of the phenolic glycosides, their aglycones, and several other compounds structurally related to the on Escherichia coli K12, Pseudomonas aeruginosa PAO1, and some strains of Staphylococcus aureus were then examined. Among them, torachrysone, toralactone, aloe-emodin, rhein, and emodin showed noticeable antibacterial effects on four strains of meth-icillin-resistant Staph. aureus with a minimum inhibitory concentration of 2-64 Ag mL. On the other hand, the phenolic compounds tested did not show strong antibacterial effects on E. coli and Ps. aeruginosa (14).

Indications Purple Star Thistle

Amenorrhea (f BOU) Anorexia (f BOU VAD) Bacteria (1 MPG) Brucella (1 MPG) Cancer (f BIB JLH) Cold (f VAD) Corns (f JLH) Diabetes (f1 MPG VAD) Dyskinesia (f VAD) Fever (f BIB EFS) Fistula (f BIB WO2) Flu (f VAD) Gallstone (f HJP) Gravel (f BIB WO2) Headache (f BOU) High Blood Pressure (1 MPG) Hyperglycemia (f VAD) Infection (1 MPG) Jaundice (f BIB) Kidney stone (f HJP) Malaria (f BOU) Mycobacterium (1 MPG) Nephrosis (f BOU HJP) Ophthalmia (f BOU) Pain (f BOU) Pseudomonas (1 MPG) Salmonella (1 MPG) Staphylococcus (1 MPG) Stone (f BIB BOU WO2) Wound (f BOU) Worm (f BOU).

Microbiological Effects

There has been interest over the years in the effects of phenylethanoid glycosides on microorganisms. Although acteoside exerted weak antibacterial effects on Escherichia coli, it had antiplasmid effects, including F'lac plasmid elimination, and inhibited kanamycin resistance transfer in E. coli (55). Similar results were observed with its isomer isoacteoside (56,57). In addition, acteoside and arenarioside exhibited a moderate antimicrobial activity against Proteus mirabilis and Staphylococcus aureus including one methicil-lin-resistant strain (58,59). The mode of action of acteoside toward Staph. aureus is related to the inhibition of leucine incorporation required for its protein synthesis. With regard to the killing kinetics, it is recognized that acteoside affects several important sites in some metabolic or structural targets on the bacterial cell (60).

Nonspecific immunotherapy Innate Immune system and cytokine

Funa has found patients with pancreatic adenocarcinomas expressing deficiencies in the NK-IFN system at least three levels (1)diminished basal NK activities, (2)decreased sensitivity of NK to IFN in virto, (3)decreased atypical IFN production by staphylococcus aureus cowan I (SACoI)(49).

Ixora chinensis Lam Rubiaceae Chinese Ixora

Chinese Ixora

Traditional Medicinal Uses The leaves are used to treat scabies, parasites and as a rubefacient for paralysis and rheumatism. 15 The fruit is used for dropsy and anasarca. 16 The seed oil is emetic, laxative, purgative and for skin ailments. 4 The latex is applied to bee and wasp stings, to dress ulcers, sores and inflamed tongues. It is also used as a haemostatic agent, 15 and to treat whitlow, carbuncle and sores in mouth. 16 The roots are used in the form of a decoction as mouthwash for bleeding gums and toothache. 15

Indications Indian Gum Arabic Tree

(f KAB WO3) Burn (f SKJ WO3) Cancer (f BIB JLH) Cancer, ear (f JLH) Cancer, eye (f JLH) Cancer, liver (f JLH) Cancer, spleen (f JLH) Cancer, testes (f JLH) Cataract (f GHA) Catarrh (f GHA HH2) Childbirth (f DEP) Chill (f ZUL) Cholecystosis (f BIB EB22 173) Cholera (f SKJ WO3) Cold (f GHA) Colic (f KAB) Condyloma (f BIB) Congestion (f BIB) Conjunctivosis (f DEP NAD) Cough (f DEP KAB NAD) Cramp (f BOU) Cystosis (f DEP) Dermatosis (f BOU WO3) Diabetes (f1 BOU DEP GHA SUW WO3 ZUL) Diarrhea (f GHA GMH PH2 SUW) Dysentery (f BIB DEP SUW) Dyslactea (1 X15283686) Dyspepsia (f ZUL) Dysuria (f KAB) Edema (1 X8982438) Enterosis (f1 DEP X15476301) Fever (f BIB BOU UPW) Flu (1 FNF) Fracture (f KAB) Fungus (1 WO3) Gastrosis (f DEP) Gingivosis (f BOU DEP PH2) Gonorrhea (f1 DEP KAB ZUL) Hemorrhoid (f BIB KAB PH2) Hepatosis (f1 BIB WO3 PR14 510 X11054840) High Blood Pressure (f1 BOU ZUL) HIV (1 X10189947) Hypersalivation (f DEP) Impotence (f NAD UPW) Induration (f BIB JLH) Infection (1 WO3 ZUL...

Clinical Features

Most children with CF present with malabsorption and failure to thrive accompanied by recurrent or persistent chest infections. In the lungs, viscid mucus in the smaller airways predisposes to chronic infection, particularly with Staphylococcus aureus and Haemophilis influenzae, and subsequently with Pseudomonas species. This leads to damage of the bronchial wall, bronchietasis, and abscess formation.

Indications Spiny Cocklebur

Bacillus (1 MPG X9364417) Bacteria (1 MPG) Blennorrhagia (f MPG) Boil (f HJP) Cancer (1 MPG) Cold (f VAD) Cramp (f VAD) Cystosis (f VAD) Diarrhea (f VAD) Dysentery (f HJP) Dyspepsia (f HJP) Dysuria (f MPG) Edema (f VAD) Epilepsy (f HJP) Fever (f VAD) Flu (f VAD) Gout (f VAD) Headache (f MPG) Hepatosis (f MPG) High Blood Pressure (f VAD) Infection (f1 MPG VAD WOI) Inflammation (f VAD) Insomnia (f HJP) Klebsiella (1 X9364417) Leukemia (1 MPG) Malaria (f EFS) Micrococcus (1 MPG) Nephrosis (f MPG) Obesity (f VAD) Oliguria (f VAD) Pain (f HJP) Pharyngosis (f MPG) Pneumonia (1 X9364417) Pseudomonas (1 X9364417) Pyelosis (f VAD) Rabies (f HJP) Rheumatism (f HJP) Salmonella (1 X9364417) Scrofula (f EFS) Snakebite (f DAW) Sore (f HJP) Sore Throat (f MPG) Splenosis (f MPG) Staphylococcus (1 X9364417) Stress (f HJP) Ulcer (f HJP) Urethrosis (f VAD) Urolithiasis (f VAD) Uterosis (f MPG) Wound (f VAD).

The Bacteria of the Colon

At birth, the colon is sterile but gradually becomes populated with microbes from maternal supply and the environment, dominated by species acquired from the mother's vaginal microbiota including Lactobaccilus, Prevotella or Sneathia spp, whereas C section babies show those of the skin surface, including the Staphylococcus genus 37 . The thick mucus lining of the colon provides a structural and metabolic support for the bacteria, partitioning the microbiota from the underlying epithelium. In diseases of the colorectal mucosa, the normal biochemistry of this human-bacterial balance is lost and is difficult to re-establish 38 .

Clinical Manifestations

Common, are usually located in the head and neck region and are often periocular. Sebaceous adenomas present as yellow papules or nodules and can be solitary or multiple (Fig. 3). Sebaceous carcinomas can be ocular or extraocular, both of which share a high risk of metastases to regional lymph nodes, bones, and viscera. Periocular sebaceous carcinomas can present as chronic blepharoconjunctivitis, recurrent chalazions, carbuncles, or painless nodules on the inner eyelid and are usually not associated with an underlying internal malignancy. However, because many patients with MTS have a sebaceous gland carcinoma, any sebaceous carcinoma must be considered as a possible marker for this syndrome.


Infections are characterized by the absence of clear local boundaries or palpable limits, which contributes to the frequent delay in diagnosis and subsequent surgical debridement. The infections may be clostridial or nonclostridial in origin. The causative agent may be a single organism, most commonly Group A p-hemolytic streptococcal infection or S. aureus, or may be polymicrobial (19). The polymicrobial infections are caused by mixed aerobic and anaerobic pathogens. Many pathogens have been described, including p-hemolytic streptococci, staphylococci, coliforms, enterococci, pseudomonads, Bacter-oides, and Vibrio vulnificus. The clinical features of NF caused by V. vulnificus are different from those of NF caused by classic pathogens when caused by V. vulnificus, especially in the warmer half of the year, the predominant skin lesions are edema and subcutaneous bleeding, and there is no superficial necrosis. Staphylococci and streptococci produce extracellular enzymes that damage...

Complications To Heart And Blood Vessels

Endocarditis, an infection of the tissues in the heart, usually a heart valve, is a progressive disease characterized by frequent embolization (obstruction of blood vessels) and severe heart-valve destruction that can be fatal if not treated. This disease can result from repeated injection of the infective agents into the blood system, usually from nonsterile needles and or unusual methods of injection. Infective endocarditis is highly prevalent among drug abusers and should be suspected in any needle-using abuser who shows such symptoms as the following fever of unknown origin heart murmur pneumonia embolic phenomena blood cultures that are positive for Candida, Staphylococcus aureus or enterococcus, or Gram-negative organisms.

Allergy and Dermatitis

Contact allergy to chemicals used in ear drops is the most common type of dermatologic otitis externa. Hairsprays, dyes, and cosmetics can also result in an eczematoid and draining otorrhea. If the source of external canal weeping is not obvious, routine patch testing is strongly suggested (20). The autoeczematization (ID) reaction, which is an autoimmune reaction that may involve only the external auditory canal, has been recorded for over 70 years in the otolaryngology literature. Recent studies confirm that this is due to a local reaction to distant fungus infections, most commonly dermatophytid in the feet and inguinal area. Control of the primary fungal infection with prolonged antifungal systemic treatment will nearly always control the ear reaction (21,22). There are other less-common dermatologic conditions that may focus on the ear. Atopic dermatitis, which has recently been found to result from a superantigen reaction to Staphylococcus aureus exotoxin, has been implicated in...

Dendritic Cell Interactions and Cytokine Production

Many of the up-regulated genes encode proinflammatory cytokines (e.g., IL-8, IL-6), and many of the down-regulated genes encode tran-scriptional factors and cellular adhesion molecules. Understanding the molecular basis of the host response to bacterial infections is critical for preventing disease and tissue damage resulting from the host response. Furthermore, an understanding of host transcriptional changes induced by the microbes can be used to identify specific protein targets for drug development. PBMC transcriptomes have been studied by using cDNA microarrays after in-vitro stimulation with killed Bordetella pertussis, Staphylococcus aureus, and Escherichia coli (Boldrick et al. 2002). This study shows a core of 205 commonly expressed genes. These genes included those with both systemic and local effects. Highly represented were genes encoding intercellular immunoregulatory and signaling molecules such as cytokines and chemokines. These genes are regulated by NFkB, which...

Amplification Based Methods Polymerase Chain Reaction

In a recent review, Niessen (2008) described the application of PCR for the diagnosis and quantification of mycotoxin-producing fungi in foods and other commodities, while Zhang et al. (2008) reported a modification of PCR using an immuno-PCR assay for the detection of shiga toxin 2 (stx2) in culture. This modification had a significant impact on sensitivity allowing detection at a level of 10 pg ml, as compared with commercial enzyme immunoassays which have a limit of detection of 1 ng ml. Ge, Zhao, Hall, and Meng (2002) reported using a combination of PCR followed by enzyme-linked immunosorbent assay (ELISA) for the detection of STEC in food. Detection limits of the assay were 0.1-10 CFU, depending on the strain type. Another modification of PCR combined restriction fragment length polymorphism (RFLP) with PCR (Atanassova, Meindl, & Ring, 2001) for the detection of Staphylococcus aureus and staphylococcal enterotoxins in pork and pork products. This method was found to be more...

Anaesthetic management

The choice of anesthetics must consider the interference pharmacokinetic benzodiazepines should be avoided for premedication propofol are the preferred induction agent morphine should be used with caution in patients with hepatic or renal function (accumulation) muscle relaxants not metabolized by hepatobiliary system (atracurium, cis-atracurium) are to be used in the first intent with adequate monitoring. The antibiotic prophilaxis (Enterobacteriaceae and Staphylococcus) is essential in this surgery. Fluid and volume therapy is an important cornerstone of treating critically ill patients in the operating room. New findings concerning the vascular barrier, its physiological functions and its role regarding vascular leakage have lead to a new view of fluid and volume administration. Avoiding hypervolemia, as well as hypovolemia, plays a pivotal role when treating patients both perioperatively and in the intensive care unit. The postoperative phase may be studded with...

Presentday Cultivation And Usage

O. fragrans flowers (known as Gui Hua or Kwei Hwa) are widely used in Chinese medicine. There are many medicinal products made from sweet osmanthus buds, leaves, and bark. They are said to protect against coughs, used to flavor other medicines, and are added to cosmetics for hair and skin. A decoction of the stem bark is used in the treatment of boils and carbuncles, and a decoction of the lateral roots is used in the treatment of dysmenorrhoea, rheumatism, and bruises. The seeds are often used as an analgesic. An essential oil obtained from the flowers is used as an insect repellent for clothes. Products are also added to herbal medicines in order to disguise obnoxious flavors (Duke & Ayensu, 1984 Manandhar & Manandhar, 2002). The essential oil of O. fragrans is considered to be one of the best natural essences, and is only used in the most expensive perfumes and cosmetics (Jin et al., 2006).

Antimicrobial And Immuneenhancing Activity

Allicin is believed to be chiefly responsible for garlic's antimicrobial activity. More specifically, it has been found to exert antibacterial activity against a wide range of Gram-negative and Gram-positive bacteria, including multidrug-resistant enterotoxicogenic strains of Escherichia coli, Staphylococcus aureus, Mycobacterium tuberculosis, Proteus spp., Streptococcus faecalis and Pseudomonas aeruginosa antifungal activity particularly against Candida albicans antiparasitic activity against some of the major human intestinal protozoan parasites such as Entamoeba histolytica and Giardia lamblia and antiviral activity (Ankri & Mirelman 1999). Ajoene is another important antimicrobial constituent, with greater antiviral activity than allien, according to one in vitro test (Weber et al 1992).

Antimicrobial And Antiparasitic

Staphylococcus aureus, Streptococcus pyogenes, S. pneumoniae and Haemophilus collected from throat swaps of Infected Individuals. The minimum inhibitory concentration of ginger ranged from 0.0003-0.7 fjg mL, and the minimum bactericidal concentration ranged from 0.135-2.04 g mL (Akoachere et al 2002). Ginger has also shown antischistosomal activity. Gingerol (5.0 ppm) completely abolished the infectivity of Schistosoma spp. (blood flukes) in animal studies (Adewunmi et al 1990). Gingerol and shogaol exhibited potent molluscicidal activity in vivo.

Choice of Neuroendocrine Hormone and Appropriate Concentration

As would seem evident, the correct concentration of catecholamine neurohormone to use in an in vitro experiment should be the level that the bacteria are likely to encounter within their host. This has two provisos firstly, the assumption that we can accurately determine the hormone concentrations at sites within the body, and secondly the assumption that bacterial pathogens will occupy just a single site during the course of an infection, and therefore will not be exposed to varying hormone concentrations. It is therefore important to realise that the concentrations of neuroendocrine hormones seen clinically are derived from fluid-based samples, such as plasma or urine, which are easy to obtain from a subject. However, the majority of the body's neurohormones are actually found in the tissue target where they act, and therefore it must be understood that the values obtained from circulatory specimens may give gross underestimates of (often several log orders lower than) the true...

Indications Frankincense

Abscess (f HAD) Alzheimer's (1 COX FNF) Anxiety (f BOW) Arthrosis (1 COX FNF) Asthma (f1 HHB X12244881) Backache (f HAD) Bilharzia (f BIB) Bleeding (f BIB HAD) Boil (f DEP) Bronchosis (f1 BIB DEP X12244881) Bruise (f HAD) Callus (f BIB) Cancer (1 COX FNF JLH) Cancer, anus (1 BIB COX) Cancer, breast (1 BIB COX) Cancer, eye (1 BIB COX) Cancer, penis (1 BIB COX) Cancer, spleen (1 BIB COX) Cancer, teat (1 BIB COX) Cancer, testicle (1 BIB COX) Carbuncle (f DEP JLH) Cerebrosis (1 X12244881) Chest ache (f BIB) Colitis (1 FNF X12244881) Congestant (f HAD) Corn (f JLH) Cough (f HAD) Crohn's Diseases (1 X12244881) Dermatosis (f GMH) Dysentery (f BIB) Dysmenorrhea (f BOW) Dyspepsia (f HAD) Edema (1 FNF) Fever (f BIB) Gingivosis (f BOW) Gonorrhea (f BIB) Hemorrhoid (f HAD) Hepatosis (1 PR14 510) Infection (f BOW) Laryngitis (f BIB DEP) Leprosy (f BIB) Leukemia (1 FNF) Mastosis (f GHA JLH) Meningioma (1 FNF) Myelosis (f HAD) Neurosis (f BIB GHA HAD) Ophthalmia (f GHA JLH) Orchosis (f JLH) Pain (f...

Activities Cedar of Lebanon

Asthma (f BIB HJP) Bacteria (1 X10548751) Bacillus (1 X10548751) Blenorrhagia (f BIB) Boil (f BIB HJP) Bronchosis (f BIB) Burn (f BIB JLH) Cancer (f BIB JLH) Catarrh (1 PH2) Cough (1 FNF HHB) Dermatosis (f BIB) Enterobacter (1 X10548751) Fungus (1 FNF) Gastro-sis (f1 x 10473175) Helicobacter (1 X10473175) Induration (f BIB JLH) Infection (f1 BIB HJP X11962214) Klebsiella (1 X10548751) Listeria (1 X10548751) Mycobacterium (1 X10548751) Phthisis (f BIB) Proteus (1 X10548751) Pseudomonas (1 X10548751) Pulmonosis (f HJP) Rash (f BIB) Respirosis (f BIB HJP) Staphylococcus (1 X10548751) Tuberculosis (1 BIB HHB).

Development of Microflora

Within the first few days and with introduction of feeding, the newborn intestine (through oxidation-reduction) promotes the establishment of aerobic bacteria, predominantly enterobacteria, Enterococcus and staphylococci, and anaerobic bacteria, bifidobacteria, Bacteroides and Clostridia. As the aerobic bacteria consume oxygen the intestinal milieu becomes more amenable to anaerobic bacteria and aerobic bacteria in turn decline. In breast fed infants bifidobacteria counts increase dramatically and account for 80-90 of the total fecal flora. Lactobacilli and Bacteroides also increase but to a lesser extent, while enterobacteria decrease. In formula fed babies Enterococcus is the predominant bacteria present with significantly less bifidobacteria and Bacteroides than the breast-fed infant. It is the difference in microflora, especially in the greater presence of bifidobacteria, and the presence of oligosaccharide and other bifido-genic factors in breast milk that likely confer a...

Main uses in food processing and perfumery

Pelargonium, essential oils (EOs), obtained from different species, with a wide spectrum of chemical compositions, have shown considerable potential as antimicrobial agents (Lis-Balchin et al., 1995). Studies have been of 18 different Pelargonium petroleum spirit extracts (Lis-Balchin et al., 1998), as well as the more hydrophylic extracts in methanol, against four bacteria Staphylococcus aureus, S. epidermidis, Proteus vulgaris and Bacillus cereus. They showed that 'Attar of Roses', similar to commercial geranium oil with the main components citronellol and geraniol, was a very potent antibactericide, as was 'Lemon Fancy', owing to its high neral and geranial content. The petroleum spirit extracts resembled the activity of steam-distilled samples. Hydrophilic extracts proved to have more potent antibacterial activity, suggesting that flavonoids, tannins and other phenolics in the herb are the effective antimicrobial agents (Lis-Balchin and Deans, 1996 Lis-Balchin et al., 1996c)....

Antimicrobial Properties of Dietary Isothiocyanates

The antibacterial effects of ITCs have been described on a number of occasions. The inhibitory effects of arylalkyl ITCs on the bacteria Escherichia coli and Bacillus subtilis are attributed to their reaction with cellular thiol groups disrupting cellular homeostasis. Indeed, the inhibition of polypeptide synthesis in the cell-free system of E. coli was attributed to the inactivation of ribosomes (43). In a study by Ono et al. identification of the active antimicrobial component in wasabi 6-methylsulfinylhexyl isothiocyanate was shown to have strong activity toward E. coli and Staphylococcus aureus (44). A comparison of the antibacterial properties of allyl isothiocyanate (AITC) with several antibacterial agents such as streptomycin, penicillin, and poly-mixin B has also been described. AITC induced a significant reduction in viability associated with the loss of membrane integrity in the bacteria S. montevideo, E. coli, and Listeria monocytogenes and was comparable to antibiotic...

Bacterial Infection

In the last decade, the acceptance of traditional medicine as an alternative form of health care and the development of microbial resistance to antibiotics have led researchers to investigate the antimicrobial activity of medicinal plants and fungi (4,5,118-120), and in vitro and in vivo animal studies of G. lucidum have been performed. Mice injected with G. lucidum extract (2 mg mouse) 1 day prior to injection with Escherichia coli showed markedly improved survival rates ( 80 compared to 33 in controls). It is not clear if this was a direct antibacterial effect or mediated by immune modulation (121). In an in vitro study, the direct antimicrobial effect of a G. lucidum water extract was examined against 15 species of bacteria alone and in combination with four kinds of antibiotics (119). The results showed that G. lucidum had antimicrobial activity against E. coli, with a minimum inhibitory concentration (MIC) of 1.75 mg mL. G. lucidum was also effective against Micrococcus luteus,...

Scaling disorders of infancy 441

Scalded skin syndrome First recognized as a distinct condition in the mid-1800s, this disease has been incorrectly called by many different names, including Ritter's disease or toxic epidermal necrol-ysis. only recently was its cause discovered to be a toxin-producing strain of Staphylococcus aureus. First symptoms usually include evidence of a primary staphylococcal infection, such as impetigo, conjunctivitis, ear infection, or sore throat with fever. The center of the face gets tender and the skin around the mouth becomes red, weeping, and crusting. The trunk also may be affected. In some patients the rash stabilizes, while in other cases flaccid blisters begin to develop all over the skin within 24 to 48 hours. Large areas of skin slough off, and hair or nails may be lost.

Bacterial and viral infections

Enterotoxigenic bacteria can produce enterotoxins that stimulate the active secretion of electrolytes into the lumen of the small intestine. This results in watery diarrhoea, which is associated with fever. Examples of enterotoxigenic bacteria are Bacillus cereus, Clostridium perfingens and Staphylococcus aureus.

Keep foods at safe temperatures

Mead et al. (1999) reported that 100 of the cases of Staphylococcus aureus, Clostridium perfringens, and Bacillus cereus illness are foodborne, but FoodNet does not conduct active surveillance of foodborne pathogens that are primarily controlled by storage temperature. Reported incidence of illnesses associated with improperly stored foods currently is low, perhaps because illnesses caused by these pathogens are largely self-limiting and medical treatment is infrequent (Mead et al., 1999), or because of the emphasis consumer education programs have traditionally placed on food handling behaviors that control these pathogens (Medeiros et al., 2001b). However, consumers frequently practice behaviors that could lead to illnesses from these pathogens. For example, a food safety survey of consumers found that almost half of the respondents were likely

Formation of an oxathiolone derivative

Chlorogenic acid, which is a common phenolic compound contained in foods and beverages, is also oxidized to its quinone form by nitrite under the acidic conditions. This quinone can be transformed to its oxathiolone derivative in the presence of thiocyanic acid as shown in Figure 13.6 (Takahama et al., 2007). A component with an oxathiolone moiety (6-hydroxy-1,3-benzoxathiol-2-one) is used for the treatment of acne, and its derivatives can inhibit the activity of carbonic anhydrase and inhibitory kB kinase-b. Oxathiolone derivatives of chal-cones can inhibit the growth of Micrococcus luteus and Staphylococcus aureus. Our results showed that the oxathiolone derivative of rutin inhibited the growth of M. luteus, but not that of E. coli, under aerobic conditions. Further studies are required to elucidate the function of oxathiolone derivatives of phenolic compounds, which may be produced in the stomach.

Origin of resistance genes

At the time antibiotics were first introduced, the biochemical and molecular basis of resistance was not known. Bacteria collected between 1914 and 1950 (the Murray Collection) were found to be completely sensitive to antimicrobial agents, including sulfanamides that had been introduced in the mid-1930s 38 . However, they contained a large number of plasmids capable of conjugative transfer. Antimicrobial resistance was reported in the early 1940s in streptococci, gonococci, and staphylococci. Recognition of the mutation of the target genes for streptomycin in M tuberculosis soon after its introduction led to the concept of multidrug therapy for tuberculosis. Staphylococcus aureus resistant to penicillin P aeruginosa resistant to -lactams gramnegative bacteria, enterococci, and staphylococci resistant to aminoglycosides

Hostpathogen factors that influence the effectiveness of antimicrobial therapy

A recent example is toxic shock syndrome (TSS) caused by staphylococcal and streptococcal superantigens 11 . Penicillin-susceptible stains of group A streptococci can cause TSS, an acute onset illness characterized by fever, rash formation, and hypotension that can lead to multiple organ failure and lethal shock despite penicillin therapy. TSS is caused by bacterial superantigens that bypass normal antigen presentation by binding to class II major histocompatibility complex molecules on antigen-presenting cells and to specific variable regions on the beta-chain of the T-cell antigen receptor. This interaction allows more rapid and intense activation of T cells, resulting in massive Th1 cytokine storm that includes an early tumor necrosis factor alpha (TNF-alpha) burst from splenic T cells during the acute cytokine response. It is this early TNF-alpha response from the cytokine storm that can lead to sepsis syndrome, disseminated intravascular coagulation, multiple organ failure, and...

Gramnegative bacillary meningitis

In contrast to tetracycline, doxycycline is highly active against S pneumoniae, including PRSP, Hemophilus influenzae, Moraxella catarrhalis, and Legionella. Doxycycline is effective monotherapy for community-acquired pneumonia 15,82-87 . It has good antistaphylococ-cal activity against MSSA but little activity against hospital-acquired MRSA (HA-MRSA). Recently, strains of community-acquired (CA) MRSA have been reported worldwide. Strains of CA-MRSA are sensitive to several commonly used antibiotics (eg, TMP-SMX, clindamycin, doxycycline) ineffective against HA-MRSA strains. Therefore, doxycycline may be used for CA-MRSA but not HA-MRSA 15 .

Susceptibility testing and the clinical microbiology laboratory

Susceptibility testing remains one of the principal functions of the clinical microbiology laboratory. If the results of in vitro susceptibility testing did not correlate with in vivo clinical effectiveness, clinicians would have no use for this information. In fact, today the clinician considers the results of susceptibility testing as being of utmost importance in directing proper antimicrobial therapy, particularly in the current era of increasing resistance. Indeed, detection of resistance has become more important as well as more difficult because of the development and spread of bacterial resistance to antimicrobial agents 38 . Unfortunately, many of these resistant phenotypes have proven difficult to detect by routine susceptibility test methods 39 . For example, proficiency-testing surveys have demonstrated that decreased susceptibility to beta-lactam agents in pneumococci and decreased susceptibility to vancomycin in staphylococci are difficult to detect 40 . In the past,...

Indications Giant Milkweed

Abscess (f HDN) Amenorrhea (f HDN) Anasarca (f DEP KAB PH2) Ancylostomiasis (f HDN) Anorexia (f DEP) Aphtha (f DEP) Apoplexy (f BOU) Arthrosis (f1 DEP HDN HJP) Ascites (f DEP PH2) Asthma (f BOU DEP KAB SUW) Bacillus (1 HDN) Bacteria (1 HDN) Bite (f KAB) Bleeding (f X15922393) Bronchosis (f DEP KAP) Cachexia (f DEP) Cancer (f1 JLH PH2 X15689169) Cancer, abdomen (f1 JLH X15689169) Cancer, liver (f1 JLH PH2 X15689169 X16688796) Cancer, ovary (f1 JLH X15689169) Cancer, skin (1 PH2 X15689169) Cardiopathy (1 FNF HDN) Caries (f HDN) Catarrh (f DEP KAB) Chancre (f HDN) Cold (f SUW) Colic (f HDN) Constipation (f DEP) Convulsion (f1 SEP PH2 X15752643) Cough (f GHA KAB PH2 SUW) Cramp (f1 DEP KAP X15752643) Dermatosis (f DEP JFM SUW) Diabetes (1 X16054794) Diarrhea (f SUW) Dropsy (f DEP HJP KAB) Dysentery (f BOU DEP HJP KAP PH2 SUW) Dysmenorrhea (f HDN) Dyspepsia (f PH2 SUW) Dyspnea (f GHA) Dystocia (f HDN) Earache (f HJP) Edema (f1 HDN X16192673) Elephantiasis (f BOU DEP SUW) Enterosis (f KAB...

Your Health Food Poisoning

Food poisoning occurs when bacteria in food are not killed before being ingested. For example, if food is left out in the summer heat, particularly anything containing dairy products, it provides an ideal growth medium for a microorganism called Staphylococcus. If food is kept refrigerated, this bacteria cannot grow and produce the chemical toxins that cause symptoms.


Multiple aspects of the immune system have been shown to be abnormal in Adamantiades-Behget's, including lowered neutrophil and endothelial cell activation thresholds, abnormal T-cell responses (including yS T-cells), increased cytokine expression and immune complex formation, increased Fas-ligand expression, abnormal complement activation proteins, and disrupted coagulation pathways (4,6). The driving process behind these multiple abnormalities is unknown. Infections have been thought to lead to the disease, and various organisms have been implicated, including Staphylococcus, Streptococcus, and some Gram-negative bacterial species, as well as multiple viruses, including herpes simplex. In most models, infection would act as the initial trigger for disease, with downstream inflammation being caused by immune cross-reactivity (7). This model is attractive, but conclusive evidence for a pathogenic role of these or other organisms has not been found (7). Antibodies reactive against oral...

Future Aspects

An ideal gene therapy vector should transduce only the desired target cells with a high efficacy. Therefore, a strong interest in developing targeted gene delivery vectors has emerged (155-162). As a first step toward targeted baculovirus transduction, Ojala et al. (163) recently described baculovirus vectors displaying either a functional single chain antibody fragment (scFv) specific for the carcinoembryonic antigen or the synthetic IgG-binding domains derived from protein A of Staphylococcus aureus. Display of the targeting moieties on the viral surface was achieved through fusion to the N-terminus of gp64 (Fig. 2) (121). Specific binding of the gp64 fusion viruses to mammalian target cells could be demonstrated by fluorescence and confocal microscopy. However, no enhancement of the viral entry or gene transfer into the mammalian cells could be observed by monitoring GFP expression. Indeed, it is well known that a specific ligand-re-ceptor interaction does not necessarily guarantee...


In animal studies the combination of ginseng polysaccharides with vancomycin resulted in a 100 survival rate for animals treated for Staphylococcus aureus compared to only 67 or 50 survival in animals treated with ginseng polysaccharides or vancomycin alone (Lim et al 2002b). A beneficial additive effect is possible but clinical use in humans has not yet been established.


Low pH Honey is an acidic substance and therefore unfavourable to the growth of certain bacteria. In vitro testing shows that Leptospermum honey can inhibit the growth of several important bacterial pathogens, including Escherichia coli, Salmonella typhimurium, Shigella sonnei, Listeria monocytogenes, Staphylococcus aureus, Bacillus cereus and Streptococcus mutans (Steinberg etal 1996, Taormina etal 2001). Honey has also been tested for efficacy against a range of drug-resistant bacteria, with positive results (Cooper et al 2002). Eighteen strains of methicillin-resistant Staphylococcus aureus and 27 strains of vancomycin-sensitive and resistant enterococci isolated from infected wounds and hospital surfaces were sensitive to concentrations below 10 w v of manuka honey and pasture honey. Artificial honey was also effective, but concentrations three times greater were required to produce similar results.

Indications Cumin

Adenoma (1 X16608205) Adenopathy (f1 JLH X16608205) Alzheimer's (1 COX FNF) Amenorrhea (f1 BOU HH2 VAD) Anorexia (f BIB VAD) Asthma (f BIB) Atherosclerosis (1 COX FNF X16608205) Bacillus (1 X10548758) Bacteria (1 X10548758 X15934015 X15631509) Bite (f DEP) Boil (f BIB KAB) Cancer (f1 JLH JAC7 405 X16608205) Cancer, abdomen (f1 JLH JAC7 405) Cancer, colon (f1 JLH JAC7 405 X16608205) Cancer, ear (f JLH) Cancer, esophagus (f1 JAC7 405) Cancer, liver (f JLH) Cancer, pancreas (f1 JNU) Cancer, spleen (f JLH) Cancer, stomach (f1 JLH JAC7 405) Cancer, testes (f JLH) Cancer, throat (f JLH) Cancer, uterus (f JLH) Cancer, uvula (f JLH) Candida (1 HH2) Cardiopathy (f1 BIB HJP X16608205) Childbirth (f HJP) Chills (f BIB) Cholera (1 HH2) Cold (f BIB BOU) Colic (f BOU BIB EGG GHA PHR PH2) Condylomata (f BIB JLH) Conjunctivosis (f BIB) Constipation (f BIB) Consumption (f BIB) Corn (f BIB JLH) Corneal Opacities (f BIB KAB) Cough (f BIB) Cramps (f BIB BOU) Debility (f NAD) Dermatosis (1 BIB JAR12 83)...

A LFbinding targets

Bovine LF could bind to the following staphylococcal species associated with bovine intramammary infections S. epidemiidis, S. warneri, S. hominis, S. xylosus, S. hyicus, and S. chromogenes (Naidu et al., 1990). The bLF-binding mechanism was specific, with affinity constants (Ka values) ranging between 0.96 mM and 11.9 mM. The numbers of bLF-binding sites per cell, as determined by using Scatchard analysis, were as follows S. epidemiidis, 3,600 S. warneri, 1,900 S. hominis, 4,100 S. xylosus, 4,400 S. hyicus, 6,100 and S. chromogenes, 4,700. The bLF- binding receptors of the six coagulase-negative staphylococcal species demonstrated marked differences in patterns of susceptibility to proteolytic or glycolytic enzyme digestion and to heat or periodate treatment. These data suggest that the bLF-binding components in S. epidemiidis and S. warneri are proteins containing glycosidyl residues. In the remaining four species, the proteinaceous nature of the bLF-binding...

Perfectionism 387

Common, the incidence of bacterial resistance increased to the point where some scientists consider it an overwhelming problem. Sometimes the extensive use of an antibiotic eliminates sensitive bacterial strains and favors the development of strains that possess natural resistance to antibiotics. This occurred with the proliferation of penicillin-resistant staphylococci. This resistance can be transferred from resistant bacteria to nonresistant forms, because genetic material tends to be shared and traded among bacteria.

Synergistic effect

Antimicrobial activities of LF were tested against 15 strains of 10 species of bacteria, and potent activities against Staphylococcus aureus, E. coli, Klebsiella pneumoniae and Proteus spp. were observed. Concomitant use of LF with antibiotic cefodoxime prox-etil resulted in a synergistic activity against S. aureus, E. coli, K. pneumoniae and Pseudomonas aeruginosa and an additive activity against E. coli strain NIHJ and Providencia rettgeri. The minimum inhibitory concentrations (MICs) of antibiotic in the presence of LF was reduced to 1 64 with an efficacy rate of 53 57 (92.9 ) in a patient group with infections (Chimura et al., 1993).

Antiviral activity

Abramson et al. (1984) suggested that the depressed chemotactic activity of PMNL infected with influenza virus could be due to changes occurring at the plasma membrane. Virus-treated PMNL stimulated with FMLP or Staphylococcus aureus exhibited a marked decrease for LF released into phagosomes, onto the cells' outer membrane, and into the extracellular medium as compared to control cells. Baynes et al. (1988) with the use of an immunoperoxidase stain for LF, showed that neutrophils in viral illness have reduced LF content compared to normal subjects. The authors suggested an acquired defect of neutrophil LF synthesis in viral infection. The LF levels in parotid saliva from

Common Names Costus

Saussurea Costus

Angina (1 PH2 JAC7 405) Anorexia (f PH2) Arthrosis (f1 KAB X12222664) Asthma (f DEP IHB PH2 SUW) Bacteria (1 HH2 PH2 X15814268) Bronchosis (f1 KAB PH2 WOI) Cancer (f HHB KAP) Cancer, abdomen (f HHB JLH) Cancer, colon (f JLH) Cancer, liver (f JLH) Cancer, spleen (f JLH) Cancer, stomach (1 X15737683) Candida (1 HH2) Cardiopathy (1 PH2 SKJ) Childbirth (f IHB) Cholera (f DEP NAD PH2 SUW) Constipation (fl IHB) Cough (f DEP KAB PH2 SUW) Cramp (f MKK) Deafness (f KAB) Dermatosis (f DEP IHB KAP PH2 SUW) Diabetes (1 JAC7 405) Dysentery (f MKK) Dyspepsia (f DEP KAP NAD) Edema (1 X12222664) Enterosis (f HHB) Epilepsy (f KAB) Erysipelas (f KAB) Fever (f IHB KAB) Fungus (f1 HH2 KAB) Gas (f1 KAB PH2) Gastrosis (1 PH2 X15737683) Headache (f KAB) Helicobacter (1 X15814268) Hepatosis (f JLH) Hiccup (f KAB KAP) High Blood Pressure (f HH2) Hysteria (f KAB) Induration (f JLH) Infection (1 HH2 PH2) Inflammation (f KAB) Insomnia (f1 NAD) Itch (f KAB) Klebsiella (1 HH2) Leprosy (f KAB KAP) Leukoderma (f...

Antiviral Effects

Antiviral activity of the mycovirus was demonstrated with avian influenza virus in primary chick embryo cells. Cytopathic effects caused by the influenza virus were inhibited when the chick cells were pretreated with a suspension of the mycovirus before exposure to influenza virus (Subha and Ng, unplublished data). The mycovirus suspension was also tested against a range of bacteria (Bacillus subtilis, Corynebacterium diptheriae, Micrococcus luteus, Streptococcus pyogenes, Staphylococcus aureus, Enterobacter aero-genes, Escherichia coli, Klebsiella pneumoniae, Salmonella typhi, Vibrio para-chaemolyticus, Bacteroides fragilis, Clostridium perfringes, and Clostridium

Indications Vetiver

MHK NAD) Colic (f WOI) Dandruff (1 JAR12 83) Dermatosis (f1 EGG MAF JAR12 83) Diabetes (1 MAF) Eczema (f MAF) Enterosis (f HOC VOD) Epilepsy (f SKJ) Fever (f JFM KAB MAF) Flu (f JFM UPW ZUL) Fungus (f1 MAF JAR12 83) Gas (f WOI) Gastrosis (f IHB MAF) Halitosis (f KAB) Hangover (f1 JAD) Headache (f JFM KAB NAD) Hemato-sis (f KAB) Hepatosis (f AHL) Infection (f1 MAF JAR12 83) Inflammation (f MAF MHK) Insomnia (f MAF) Lumbago (f WOI) Malaria (f MAF SKJ ZUL) Mycosis (f1 EGG MAF JAR12 83) Nausea (f MHK) Nesseria (f MAF) Neuralgia (f HOC JFM) Neurosis (f MAF) Odontosis (f MAF) Pain (f MAF VOD) Palpitation (f NAD) Parasite (f VOD) PID (f MAF) Pleurisy (f JFM UPW ZUL) Puerperium (f IHB) Rheumatism (f JFM WOI) Septicemia (f MAF) Snakebite (f SKJ) Spermatorrhea (f KAB) Sprain (f WOI) Staphylococcus (f1 MAF X10438227) Stings (f SKJ) Stomatosis (f MAF SKJ) Toothache (f MAF) Trichophyton (1 JAR12 83) UTI (f MAF) Vomiting (f WOI) Yellow Fever (f UPW).


Essential oil from the root induced glutathione-s-transferase activities in the stomach, liver and small intestine of mouse. An ethanol extract of dried rhizome showed antispasmodic activity vs histamine-induced contraction and barium-induced contraction in Guinea pigs. An ethanol-water extract indicated smooth muscle stimulant activity. Water extracts of dried rhizomes exhibited antitumour activity. Rhizome and root oils showed antibacterial activity against Escherichia coli, Staphylococcus aureus and antifungal activity against Cladosporium sp. Nematocidal activity was observed in the rhizome of K. galanga.


Cephalosporin dihydrothiazine ring is replaced by a methylene group (cf. carbapenems, Section Loracarbef is highly active against Gram-positive bacteria, including staphylococci, but shows poor activity against Gram-negative bacteria. The general structure of the 2-deoxystreptamine-containing antibiotics (the aminoglycoside antibiotics) is shown in (11.89), together with examples of the different drugs. Streptomycin (11.90) does not contain 2-deoxystreptamine. The more important aminoglycoside antibiotics are kanamycin (11.27), gentamicin (11.91), tobramycin (11.92), amikacin (11.28), sisomicin (sissomicin) (11.93) and netilmicin (11.94). As a group, the aminoglycoside antibiotics are bactericidal to Gram-negative bacteria and to staphylococci. Two of the major problems, however, have been the development of resistance of Gram-negative bacteria, often by virtue of drug-modifying enzymes (acetyltransferases, adenylylating enzymes and phosphotransferases see Section

Indications Garlic

LIB TGP) Bacillus (1 LAW X10548758) Bacteria (1 JFM PH2) Bite (f FAY JFM) Boil (f1 DAA) Bronchiestasis (1 KAL) Bronchosis (f12 FAD PHR PH2 BOD WHO) Burn (f12 KAL) Callus (f JFM PH2) Cancer (f12 AKT FAD PH2) Cancer, abdomen (f1 AKT FNF JLH) Cancer, bladder (f1 FNF JLH X11341051 X11238811) Cancer, breast (f1 BRU JN131 989s) Cancer, colon (f1 AKT (f1 FNF JLH)) Cancer, esophagus (f1 JN131 1075s) Cancer, gland (1 X11238818) Cancer, liver (f1 BO2 PR14 564) Cancer, lung (f1 BRU FNF JLH JN131 989s) Cancer, prostate (f1 X11102955) Cancer, skin (f1 FNF JLH) Cancer, stomach (f1 AKT VOD X11238811) Cancer, uterus (f1 FNF JLH) Candidiasis (f12 CAN KAL TRA VOD) Carbuncle (f FAY) Cardiopathy (f123 BGB EGG FAD SKY VOD) Caries (f1 FNF KAB) Catarrh (f1 AKT BGB) Celiac (1 KAL) Chilblain (f EGG) Childbirth (f JFM KAB) Cholecocystosis (f APA) Cholera (f1 PNC TRA) Chronic Fatigue (f JFM) Circulosis (f DLZ) Coccidiosis (1 KAL) Cold (f12 AKT FAD GHA PHR PNC) Colic (f1 GHA WHO) Colosis (1 KAL LAW) Congestion...

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