Other Th1Mediated Skin Diseases in Which Testing of Anticytokine Therapy Is Warranted

Other skin diseases that appear to involve a Th-1-mediated immune response include seborrheic dermatitis (SD), rosacea, oral lichen planus, and dermatophytosis. SD has upregulated expression of proinflamma-tory cytokines in skin biopsies of SD lesions (Molinero et al. 2003). T-cell subsets are also found in the dermal infiltrates of rosacea lesions (Rufli and Buchner 1984), and IFN-y-producing cells are found in dermatophytosis (Koga et al. 2001). In oral lichen planus, mononuclear cells express IFN-y in the superficial lamina propria (Khan et al. 2003). Our near-term goal is to test anticytokine therapy in these conditions.

How To Deal With Rosacea and Eczema

How To Deal With Rosacea and Eczema

Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.

Get My Free Ebook


Post a comment