Conclusion

Despite all recent developments in cancer diagnosis and therapy, PC still remains one of the leading causes of cancer related deaths in men. Nevertheless, designed new tools for precise diagnosis will enable researchers to distinguish patients "who will be recurred earlier, but will require more extensive treatments" from those "who will have lifespan less effected from their disease". Unlike some other solid tumors, PC is one of these tumor types in which limited treatment options are available so far and gain of drug-resistance is seen more often. That is why there is an urgent need for alternative and novel therapies.

CSCs are believed to be a subpopulation of cancer cells that modulate malignancy and show resistance to current anticancer treatments, which make them indicators of poor prognosis. There are still many aspects of CSCs that remain to be discovered; like, which main mechanisms regulate normal SC function and how are they used by malignant cells to propagate the disease? A careful dissection of the main differences between normal adult SCs and CSCs as well as of their overlapping aspects are important to distinguish how cancers proceed. Transforming the gained knowledge in CSC biology into effective therapies would then help patients to regain their health much earlier. Altogether, that is the reason why the relation between the expressed CSC markers and resulting malignant behavior needs to be sufficiently understood, as they are primarily relevant with the prognosis of cancer.

10 Ways To Fight Off Cancer

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