Effects on Sleep Quality

Sleep disturbance is common among patients with chronic bronchitis and asthma. Sleep disturbance in children with asthma is associated with psychological problems and impairment of memory (59). Among patients with COPD, 41% reported at least one symptom of disturbed sleep (60), possibly contributing to nocturnal oxygen desaturation, the development of pulmonary hypertension, polycythemia, and cardiac arrhythmias (61,62). A randomized double-blinded study involving 36 patients with moderate to severe COPD showed that ipratropium increased total sleep time, decreased the severity of nocturnal desaturation, and improved the patient's perceptions of sleep quality (63).

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