Various demographic and disease variables predict PDD (Table 3). More recent work suggests that neuropsychological evaluation may also facilitate early identification of PDD. Jacobs et al. (91) and Mahieux et al. (92) noted that poorer performance by
Greater age Lower education
Later onset Disease duration
Diminished cognitive test performance: Executive/Attention Verbal fluency Visuoperceptual List learning
Lower socioeconomic status Family history of Parkinson's dementia
Disease severity Susceptibility to levodopa-induced psychosis or confusion patients with PD on verbal fluency, attentional, and visuospatial tasks was associated with subsequent development of dementia. Woods and Tröster (93) found that nondemented PD patients who met criteria for dementia at one-year follow-up evaluation demonstrated poorer baseline performance on measures of word-list learning and recognition, complex auditory attention, and executive function.
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