Recent positron-emission tomography (PET) scan data (18) have demonstrated functional reorganization of speech-motor areas within the brain following the LSVT®. Treatment-related changes were found in the right globus pallidus (GP) and in the supplementary motor area (SMA). In the GP resting state, rCBF was significantly reduced post-treatment when compared with pre-treatment and significantly increased during sustained phonation when compared with rest. The authors concluded that the LSVT® reduced baseline GP overactivity, resembling the effect of pallidotomy. However, the LSVT® increased GP activity during vocalization. These findings document the neural basis for behavioral changes following the LSVT®.
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