Additional factors including patient age, performance status, CA-125 levels, histology, tumor grade, and others have also been evaluated in an attempt to predict which patients will benefit from surgery. None of these factors has been shown to significantly influence the results of secondary cytoreduction independently of the other more robust factors previously mentioned.
It is notable that DESKTOP investigators found that both performance status and residual disease after primary surgery were associated with the probability of achieving complete resection during secondary cytoreduction. However, neither factor was associated with survival.
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