Cytoreductive surgery is one of the cornerstones of therapy for advanced-stage ovarian cancer. Complete tumor removal and microscopic residual disease seem to offer the best survival outcomes.
Secondary cytoreductive surgery should be reserved for patients with prolonged disease-free interval and localized disease.
Second-look surgery does not result in improved survival.
Accurate and complete surgical staging is the foundation of therapy for early-stage ovarian cancer.
Fertility sparing and minimally invasive surgery are often practicable in young women with early-stage ovarian cancer without untoward effects on survival.
Frozen-section analysis is accurate in the diagnosis of ovarian cancer but is less reliable in the diagnosis of borderline ovarian tumors.
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