Key Points

There is no effective screening test for ovarian cancer.

Both pregnancy and oral contraceptive use reduce the risk of ovarian cancer in the general population.

In the general population, the benefits of prophylactic oophorectomy are modest and must be considered against the implications of surgical menopause. Approximately 10% of ovarian cancers are hereditary.

The majority of studies support the use of oral contraceptives for the prevention of ovarian cancer in women with a high risk for developing ovarian cancer.

Prophylactic oophorectomy should be considered in women at high risk for ovarian cancer after the age of 35 or once childbearing is complete.

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