• Brassica vegetables have long been a part of the human diet, and, aside from being a good source of vitamins and minerals, they also contain phytochemicals that are beneficial for human health.
• Broccoli contains the highest level of glucoraphanin amongst commonly consumed Brassica vegetables, with broccoli seed and sprouts containing the highest levels during the life cycle.
• There is strong evidence that sulforaphane derived from glucoraphanin is protective against cancer for many individuals.
• Diet—genotype interactions still need to be better explored to determine how this benefit is mediated.
• Glucoraphanin is well tolerated in both animal and human studies at normal dietary levels, with no serious adverse reactions reported.
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