• Watermelon (Citrullus lanatus) cultivation and the marketing of fruits and seeds are relevant to the nutritional and therapeutic needs of modern lifestyles, as the seeds offer nutraceutically valued oils.
• An additional advantage is the use of watermelon seed oil in cosmetic preparations (cosmoceuticals).
• The abundance of triglycerides (TG), saturated fatty acids (SFA), and u-6 polyunsaturated fatty acids (PUFAs) meet cooking, cosmetic, and therapeutic oil needs.
• Watermelon seed oil is a popular medicinal and clinical source of u-PUFAs used in treating coronary heart diseases (CHD), where it is operative at the epithelial and membrane levels.
• The intermediates of linoleic acid and a-linolenic acid cascades could be useful in gene technology.
• Watermelon seed oils rich in linoleic acid (LA) play a vital role in treating nervous, endocrine, and immunological disorders, through PUFA's metabolism.
• Watermelon seed oil, made into emulsions, could also be administered to give an effective and controlled supply or dosage of LA for therapeutic purposes.
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