Summary Points

• Guava plants are found worldwide and are used medically to, for example, control diarrhea, reduce inflammation, and decrease antibacterial activity.

• A new antimicrobial peptide from guava seeds has been identified and characterized.

• Guava seed peptide belongs to the glycine-rich protein group, a family earlier described only as storage proteins.

• In vitro bioassays showed that P. guajava antimicrobial peptide was able to inhibit the growth of gram-negative bacteria causing gastrointestinal infections in human.

• The peptide herein described could be used, in the near future, as a novel tool in the treatment of infections caused by Proteus sp. and Klebsiella sp., also delaying the process of bacterial resistance toward currently used medicines.

• The action mechanism of P. guajava antimicrobial peptide seems to be by pore formation in the cell membrane when in a homodimer conformation.

Was this article helpful?

0 0
Health And Fitness 101

Health And Fitness 101

Self-improvement is a thing which you must practice throughout your life because once you started to believe that you are perfect then, things will start to become complex. You need to know that no one is perfect and no one can be perfect.

Get My Free Ebook


Post a comment