Summary Points

• Sophora moorcroftiana is an endemic shrub species in Tibet altiplano, PR China, and there are one to seven seeds in the pods when the seeds ripen, between August and October.

• The ripe seeds are used as medicine, and the decoction of 9 g seeds is used in Chinese folk medicine for dephlogistication, detoxication, as an emetic, in infectious diseases, and in verminosis.

• The EE95 LC50 of the cytotoxicity in tumor cells is 1.4 mg/ml, which is the lowest among all crude extracts.

• The EE95 and alkaloids inhibit the proliferation of and induce apoptosis in tumor cells in a concentration-dependent manner in vitro.

• The EE95 inhibits the tumor tissue growth, and the inhibition rate when treated with EE95 (800 mg/kg per day) was 28.1% in vivo.

• The EE95 may exert its antitumor effect via inducing tumor cell necrosis and lymphocyte soakage in tumor tissue in vivo.

• The EE95 could enhance the self antitumor response, and stimulate the secretion of TNF-a and IL-2 by immune cells in vivo.

• The EE95 from SM seeds possesses potential antitumor fraction(s) in animals.

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Health And Fitness 101

Health And Fitness 101

Self-improvement is a thing which you must practice throughout your life because once you started to believe that you are perfect then, things will start to become complex. You need to know that no one is perfect and no one can be perfect.

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