Bitter kola seed is chewed principally for health maintenance or curative reasons, and its therapeutic efficacy has gained universal acceptance. The tree is still sparsely cultivated, because seedling growth is slow, and natural regeneration of the species is poor. This consequently results in low production of the seed during harvest. However, the extensive potential of GK seed against a spectrum of disease conditions should renew interest in the domestication of the species for effective utilization for public health management. In addition, the bitterness inherent to GK seed could be exploited as a substitute for hops.
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