Sea buckthorn (Hippophae rhamnoides L.), a multipurpose plant with exceptionally high contents of nutrients and phytochemicals, grows naturally in various regions of Asia and Europe. Sea buckthorn seed oil contains a number of bioactive substances, namely vitamins, carotenoids, sterols, and polyunsaturated fatty acids (PUFAs). A wide spectrum of pharmacological effects of sea buckthorn seed oil have been reported, including anti-oxidative, anti-microbial, anti-atherogenic and cardioprotective, hepatoprotective, radioprotective, and tissue regenerative. Recent studies have reconfirmed the traditional therapeutic use of sea buckthorn seed oil for burns, ulcers, mucosal injuries, and other skin diseases. No toxicity or adverse reactions have been reported after oral or topical application of sea buckthorn seed oil.
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