Sage is likely to be safe when taken in amounts typically found in foods, although sage oil contains thujone, which may be toxic in large doses. In large amounts, the camphor and thujone content of sage oil have been shown to have convulsant properties in rats (Millet et al 1981) and when taken internally in large amounts, sage may cause restlessness and seizures in humans (Blumenthal et al 2000, Newell et al 1996). Sage tea has also been reported to cause cheilitis and stomatitis, dry mouth and local irritation.

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