Significant Interactions

Controlled studies are not available; therefore, interactions are based on evidence of activity and are largely theoretical and speculative. ANTICOAGULANT AGENTS

Red clover contains coumarin, which could theoretically exert anticoagulant activity and therefore increase the clinical effects of warfarin. However, it is only the byproduct, dicoumarol (produced by microorganism in poorly dried sweet clover) that has established anticoagulant effects. Interaction with anticoagulant medication is not likely for extracts from properly dried red clover. Observe patients taking red clover and anticoagulants concurrently.

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