Significant Interactions

Controlled studies are not available, so interactions are based on evidence of activity and are largely theoretical and speculative. DOPAMINE ANTAGONISTS

An antagonistic interaction is theoretically possible — observe patients. ORAL CONTRACEPTIVES

There has been speculation about the effectiveness of vitex when OCP are being taken. Several clinical studies involving women taking oral contraceptives have confirmed the herb still reduces PMS symptoms and does not affect OCP.

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