Shark cartilage

Historical note Shark cartilage became a popular supplement in the 1980s, largely based around the claim that sharks rarely get cancer and therefore must have some protection against the disease. By 1995, the annual world market for shark-cartilage products exceeded US$30 million and dozens of shark cartilage products were available in retail stores and usually sold as food supplements (Ernst 1 998). Over the past few decades, some progress has been made in identifying the various unusual compounds present in shark cartilage and it is clearly known that it contains some anti-angiogenic compounds, which increase resistance to tumours. Previously, much work had been conducted with bovine cartilage, which also exhibits anti-angiogenic properties, although to a lesser extent.

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