Rheuma Toid Arthritis

One study has suggested that patients with higher pain scores and active disease are at significantly greater risk of riboflavin deficiency than those with inactive disease (Mulherin et al 1996). In this study of 91 patients, pain score, articular index, C-reactive protein, and erythrocyte sedimentation rate were all increased in those patients exhibiting riboflavin deficiency (all P < 0.02). It is unclear whether riboflavin deficiency influences pain threshold or is a result of the disease.

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