Historical note Pygeum africanum is a large, evergreen tree native to Africa. Its bark has been used medicinally for thousands of years by traditional African healers to treat bladder disorders, kidney disease, prostate disorders, and malaria, as well as male baldness and to enhance sexual functioning. Since the late 1960s, the extract has been used in clinical practice in Europe; however, because of over-harvesting, the plant is now considered an endangered species and efforts are underway to protect it.
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