Premenstrual Syndrome

Although tyrosine is used to reduce symptoms of irritability, depression, and fatigue Tyrosine 1175

associated with PMS, this is largely based on theoretical considerations and the

observation that a significant reduction in tyrosine levels occurs during the premenstrual period according to one study (Menkes et al 1994).

This study further found that tryptophan depletion caused a significant aggravation of premenstrual symptoms, particularly irritability, and symptom magnitude was correlated with reduction in tryptophan relative to other amino acids.

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