Pregnancy Use

Safety is unknown for high-dose supplements; however, dietary intake levels are safe.

PRACTICE POINTS/PATIENT COUNSELLING

• L-Lysine is an essential amino acid found in foods such as animal proteins, eggs and milk.

• It has been shown to inhibit HSV multiplication in vitro.

• Supplemental L-lysine is popular as a prophylactic and treatment for HSV.

• Studies have yielded inconsistent results suggesting that there may be individual variation in responses.

• Doses used as prophylaxis range from 1000-3000 mg/day with treatment doses generally above 3000 mg/day.

• L-Lysine may also enhance intestinal absorption of calcium and reduces its renal excretion.

ANSWERS TO PATIENTS' FREQUENTLY ASKED QUESTIONS

What will this supplement do for me?

L-Lysine supplements may reduce the frequency and severity of herpes simplex outbreaks. It may also improve the way the body absorbs and retains calcium. When will it start to work?

Studies suggest that several months' treatment may be required, with a long-term approach recommended. Are there any safety issues?

L-Lysine appears to be a very safe supplement, although safety has not been established in pregnancy and lactation for high-dose supplements.

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