A chalcone flavonoid, xanthohumol and a flavone isomer of xanthohumol found in hops act as antiproliferative agents in vitro (Miranda et al 1999, Stevens & Page 2004). In vitro data has demonstrated that hops induces detoxification enzymes, in particular quinone reductase, which may contribute to its chemoprotective effects (Dietz et al 2005). A review concluded that this compound has the ability to protect in the initiation, promotion and progression stages of cancer (Gerhauser 2005b).
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