Peripheral Vascular Disease

Due to its anti-ischaemic activity, l-carnitine supplements have also been used in peripheral vascular disease. A double-blind crossover study supports this use, finding l-carnitine supplements (2 g/day) taken for 3 weeks increased walking time in people with peripheral vascular disease (Brevetti et al 1988). A derivative of l-carnitine, known as propionyl-l-carnitine, taken for 6 months (2 g/day orally) has also demonstrated significant improvements in walking distance and speed in patients with claudication (Hiatt etal 2001).

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