Optic Neuropathy

Several case reports suggest this condition can be caused by thiamine deficiency and successfully treated with supplementation. One case report of a man developing optic neuropathy as a result of receiving TPN without thiamine for 4 weeks found that supplementation with thiamine reversed the condition (Suzuki et al 1997). Two cases of symmetrical, bilateral optic neuropathy associated with thiamine deficiency were successfully treated with thiamine supplementation (Hoyt & Billson 1979).

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