Vitamin D maintains muscle strength and has an effect in skeletal muscle and myocardial function. Although it has been established that skeletal muscles have receptors for vitamin D, the specific actions of this steroid on muscle are largely unknown. Recently a link between fibromyalgia and vitamin D deficiency has been suggested, with an estimation of 40-60% of cases presenting with generalised muscle weakness and pain being undiagnosed hypovitaminosis (Holick 2004). Vitamin D 1311

Through unidentified mechanisms vitamin D exerts a direct effect on the myocardium:

1,25-(OH)2D3 controls hypertrophy In cardiac monocytes and, together with 25-OHD, Improves the left ventricular function In patients with cardiomyopathies (Brown etal 1999).

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