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Most investigation has been conducted with one of two commercial preparations Seatone or Lyprinol. ANTI-INFLAMMATORY

Significant anti-inflammatory activity has been observed in both humans and animals with NZ green-lipped mussel (Halpern 2000, Miller & Ormrod 1980, Miller et al 1993). The mechanism of action is not well understood, but results from test tube and animal studies suggest inhibition of leukotriene B4 synthesis and PGE2 production by activated macrophages and prostaglandin inhibitor actions (Miller & Wu 1984, Miller etal 1993).

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