Intermittent Claudication

A Cochrane review of five placebo-controlled studies including a total of 265 volunteers (average age 57 years) concluded that although further research is required to determine its effectiveness, vitamin E may have beneficial effects in intermittent claudication with no serious side-effects (Kleijnen & Mackerras 2000). Treatment duration varied from 12 weeks to 18 months and dosage regimens varied between the studies, which were considered generally small and of poor quality. A closer look at the evidence suggests that doses of at least 600 lU/day for a minimum of 12 weeks are required.

More recently, a randomised, double-blind study found no benefits with vitamin E (400 lU/day) on perceived pain or treadmill walking duration in people with claudication (Collins et al 2003).

A small study of 16 patients with stable claudication revealed that administration of vitamin E (200 mg/day) and vitamin C (500 mg/day) for 4 weeks reduces oxidative stress in this population and therefore may also have an effect on the remote ischaemia-reperfusion damage (Wijnen et al 2001).

How To Keep Your Treadmill Running

How To Keep Your Treadmill Running

Buying a treadmill is hard enough. Choosing the best out of many treadmills in the market is nigh impossible. But once youve got the treadmill youve always wanted, are your worries truly over? Well, they certainly are, but only if you maintain your treadmill properly.

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