Info

Vitamin E

Reduced side-effects

Beneficial Interaction possible

One study found that oral DL-alpha tocopheryl acetate (1600 lU/day) prevented doxorublcln-lnduced alopecia; however, the same dosage failed to prevent alopecia after doxorubicin treatment after mastectomy for breast cancer

Antimetabolites

Methotrexate

Folate

Reduced side-effects but may reduce drug response

Caution In cancer treatment Observe In other conditions

Methotrexate Is a folate antagonist drug, supplementation may reduce toxicity. This action may be problematic In cancer treatment and reduce drug response, but beneficial In other uses

Paclltaxel

Licorice

Additive effects

Observe

A constituent of licorice has been demonstrated to significantly potentiate the effects of paclltaxel In vitro — clinical significance for licorice unknown

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