Info

Vitamin B2 (riboflavin)

Decreased B2 levels

Monitor for signs and symptoms of B2 deficiency

Beneficial interaction possible

Tricyclic antidepressants may reduce the absorption of riboflavin. Increased B2 intake may be required with long-term therapy

Drug

Herb/Supplement

Potential outcome

Recommendation

Evidence/Comments

Imipramine

Vitamin B3 (niacin)

Additive effects

Beneficial Interaction possible

A combination of Imlpramlne with L-tryptophan 6 g/day and niacinamide 1500 mg/day has been shown to be more effective for people with bipolar disorder than Imlpramlne alone

Antipsychotic agents

Haloperidol (e.g. Serenace)

Ginkgo biloba

Increased drug effects and reduced side-effects

Observe — beneficial Interaction possible under professional supervision

Three clinical trials demonstrate that ginkgo Increases drug effectiveness

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