Vitamin E

Increased bruising and bleeding

Caution with high-dose supplements (>1000 III dally)

Until clinical significance can be established prothrombin time or INR should be closely monitored with addition or withdrawal of highdose vitamin E supplements

Clinical studies have produced conflicting results: several found no effects of platelet aggregation or coagulation, although others found an Increased bleeding risk

People with reduced levels of vitamin K may be more susceptible to the effects of vitamin E potentiating warfarin activity

Antiplatelet drugs (e.g. aspirin)


Increased bruising and bleeding


Herb Inhibits platelet aggregation, observed In animal and clinical studies

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