Info

Vitamin/ mineral

Australian and New Zealand RDI for adults

(>18yo)

Dose range used in practice

Major uses

(oral or topical forms)

Cautions

Side-effects

Toxicity

Selenium

Women: 60/ig Men: 70/ig

80-200 /ig/day

Treating deficiency Prevention of secondary deficiency (e.g. cirrhosis, malabsorption syndromes, cystic fibrosis, coeliac disease, HIV infection) Reducing total cancer incidence and mortality (especially lung, colorectal and prostate cancers), adjunctive treatment HIV infection Cardiovascular disease Autoimmune thyroiditis Symptoms of RA, asthma Male infertility Anxiety and depression

Hypersensitivity NHMRC upper level of intake is 400 /ig/day

Nausea, vomiting, nail changes, irritability, fatigue

Organic form of selenium found in high-selenium yeast is less toxic and safer than other forms

Long-term use of excessive doses (>1000/ig/day) can produce fatigue, depression, arthritis, hair or fingernail loss, garlicky breath or body odour, gastrointestinal disorders and irritability

Vitamin/ mineral

Australian and New Zealand RDI for adults

(>18yo)

Dose range used in practice

Major uses

(oral or topical forms)

Cautions

Side-effects

Toxicity

Zinc

Women: 8 mg Men: 14 mg

25-200 mg/day

Treating deficiency Prevention of secondary deficiency (e.g. cirrhosis, malabsorption syndromes, severe burns, majorsurgery) Treating the common cold and reducing symptoms (lozenges) Diabetes

Enhancing wound healing (e.g. leg ulcers) Decreasing relapse rates In Crohn's disease Acne vulgaris Topical: herpes simplex Infection

Hypersensitivity

Mild gastrointestinal upset at doses of 50-1 50 mg/day

Single doses of 225^50 mg usually Induce vomiting Nausea, vomiting, diarrhoea, fever and lethargy, which have been observed after Ingestion of 4-8 g Doses ranging from 100 to 150 mg/day Interfere with copper metabolism and cause hypocupraemla, red blood cell mlcrocytosls, and neutropenia If used long-term

ER, extended release; yo, years old.

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