Increased potassium excretion

Avoid long-term use unless under medical supervision Monitor potassium status

Potassium loss may become significant when licorice is used in high dose (>100 mg glycyrrhizin daily) for longer than 2 weeks

Loop diuretics


Increased magnesium excretion

Monitor magnesium efficacy and status — beneficial interaction possible

Increased magnesium intake may be required with long-term therapy

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