Info

Vitamin B6 (pyridoxine)

Reduced vitamin B6 absorption

Separate doses by at least 2 hours

A clinical trial has shown that the drug may induce B6 deficiency, so increased intake may be required with long-term therapy

Methyldopa (e.g.Aldomet)

Coenzyme Q10

Reduced CoQ10 serum levels

Beneficial interaction possible

Increased CoQ10 intake may be required with long-term therapy

ACE inhibitors (e.g. captopril, enalapril)

Iron

Reduced drug effect

Separate doses by at least 2 hours

Asmall clinical trial found that concomitant iron administration reduced area-under-the-curve plasma levels of unconjugated captopril by 37%

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