Immunostimulant Effect

It is reported that dong quai can counter the immunosuppressive effects of hydrocortisone in vivo (Mills & Bone 2000). Immunostimulation is further suggested by in vitro studies demonstrating enhanced cell mediated immunity (Yang et al 2005a) and upregulation of IL-2 and IFN-gamma (Yang et al 2005a), as well as nonspecific lymphoproliferation (Wilasrusmee et al 2002). A polysaccharide from dong quai has also been found to enhance non-specific immunity while suppressing humoral immunity (Yang et al 2003).

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