Adhatoda vasica leaf (50-100 mg/kg) was shown to protect against induced liver damage in rats (Bhattacharyya et al 2005); 100 mg/kg of Adhatoda vasica was comparable to the hepatoprotective ability of silymarin at 25 mg/kg. An earlier study showed that Adhatoda vasica (100-200 mg/kg) protected against carbon tetra-chloride-induced liver damage in rats (Pandit et al 2004). The leaf extract significantly enhanced the protective enzymes superoxide dismutase and catalase in the liver: 200 mg/kg of Adhatoda vasica was shown to be comparable to 25 mg/kg of silymarin.

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