A double-blind study involving 75 patients with eye strain caused by viewing a computer screen found that GSE 300 mg daily significantly improved objective and subjective measures (Bombardelli & Morazzoni 1995). Grapeseed extract (Endotelon'®) has also been shown significantly to improve visual adaptation to and from bright light in a dual centre study involving 100 volunteers (Boissin et al 1998, Corbe et al 1988). A dose of 200 mg daily over 5 weeks was used. It has been proposed that GSE increases rhodopsin content of the retina or accelerates its regeneration after exposure to bright light.
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