Deficiency Signs And Symptoms

Vitamin B12 deficiencies manifest primarily as haematological and neurological disturbances, and are estimated to affect 10-15% of individuals over the age of 60 years (Baik & Russell 1999):

• Haemotological: macrocytic (megaloblastic) anaemia, pancytopenia (leukopenia, thrombocytopenia); symptoms may include lethargy, dyspnoea, anorexia, weight loss and pallor (Wahlqvist 2002).

• Neurological disturbances: paraesthesias, optic neuropathy (reversible), peripheral neuropathy and demyelination of the corticospinal tract and dorsal columns (subacute combined systems disease).

• Psychological disturbances: impaired memory, irritability, depression, personality change, dementia and psychosis (Lee 1999, Lindenbaum et al 1988).

• Various gastrointestinal symptoms can also develop, such as loss of appetite, intermittent constipation and diarrhoea, glossitis and abdominal pain.

• Folic acid supplementation may mask an underlying B12 deficiency, leading to the progression of neurological symptoms.

Lower Your Cholesterol In Just 33 Days

Lower Your Cholesterol In Just 33 Days

Discover secrets, myths, truths, lies and strategies for dealing effectively with cholesterol, now and forever! Uncover techniques, remedies and alternative for lowering your cholesterol quickly and significantly in just ONE MONTH! Find insights into the screenings, meanings and numbers involved in lowering cholesterol and the implications, consideration it has for your lifestyle and future!

Get My Free Ebook


Post a comment