Cognitive Function

Lemon balm has been used for centuries to Improve cognitive function and encouraging results from a 2002 clinical study confirm that it can influence memory.

The randomised, double-blind crossover study involving 20 healthy young volunteers found that single doses of lemon balm were able to modulate both mood and cognitive performance in a dose- and time-dependent manner (Kennedy et al 2002). In this study, treatment with the lowest dose (300 mg) increased self-rated 'calmness' within 1 hour whereas the 600 mg and 900 mg doses produced significant effects on memory task performance, observable at both 2.5 hours and 4 hours after administration. The highest tested dose (900 mg) was found to significantly reduce alertness within 1 hour, suggesting a dose-response effect.

ALZHEIMER'S DISEASE

A randomised, double-blind, placebo-controlled trial demonstrated the efficacy and safety of M. officinalis in 42 patients aged 65-80 with mild to moderate Alzheimer's disease who were given 60 drops/day for 4 months (Akhondzadeh et al 2003). Outcome measures included significantly better cognition and reduced agitation.

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