Clinical Use

The therapeutic effectiveness of dandelion has not been significantly investigated under clinical trial conditions, so evidence is derived from traditional, in vitro and animal studies. DIURETIC

Dandelion has a long history of use as a diuretic in well-established systems of traditional medicines; however, the scientific and clinical evidence to support this use is limited to animal studies (see above). The high potassium content of dandelion is considered to be partly responsible for any diuretic activity (Hook et al 1993).

A double-blind randomised study of 57 women with recurrent cystitis found that a commercial preparation known as Uva-E (a combination of Arctostaphylos leaves and dandelion root) significantly reduced the frequency of recurrence of cystitis compared with placebo. At the end of 12 months, none of the patients taking Uva-E had had a recurrence of cystitis, compared with 23% recurrence in the control group (P < 0.05) (Larsson et al 1993). The role of dandelion in achieving this result is unknown; however, the researchers suggested that its diuretic effect was likely to have contributed to the positive results.

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