Clinical Use

Although vitamin E supplementation is used to correct or prevent deficiency states, most uses are based on the concept of high-dose supplements acting as therapeutic agents to either prevent or treat various health conditions. DEFICIENCY: PREVENTION AND TREATMENT

Traditionally, vitamin E supplementation has been used to treat deficiency or prevent deficiency in conditions such as genetic abnormalities with alpha-tocopherol transfer protein, apolipoprotein B, or microsomal triglyceride transfer protein (Shils et al 1999); and fat malabsorption syndromes (e.g. chronic cholestasis, cystic fibrosis, short bowel syndromes such as Crohn's disease, chronic steatorrhea, coeliac disease, chronic pancreatitis and TPN).

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