Chronic Fatigue Syndrome

Studies investigating whether people with CFS have lower levels of free l-carnitine have shown contradictory results (Jones et al 2005), and trials using l-carnitine supplementation in CFS have generally produced mixed results (Plioplys & Plioplys 1995, 1997, Soetekouw et al 2000). One randomised controlled trial did find that 1 g l-carnitine (three times daily) produced a significant clinical improvement, especially between the fourth and eighth week of treatment (Plioplys & Plioplys 1997).

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