Arterial And Venous Leg Ulcers

A 2000 Cochrane review assessed six placebo-controlled trials of zinc sulfate supplementation in arterial and venous leg ulcers and concluded that overall there is no evidence of a beneficial effect on the number of ulcers healed. However, there is some evidence that oral zinc might improve healing of venous ulcers in people with low-serum zinc levels (Wilkinson & Hawke 2000).

Double-blind studies producing encouraging results have used oral zinc (600 mg/day) combined with topical treatment and compression bandages (Haeger & Lanner 1974, Hallbook & Lanner 1972).

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